Abstract: Novel polypeptides, designated Apaf-1, which are capable of modulating apoptosis are provided. Compositions including Apaf-1 chimeras, nucleic acid encoding Apaf-1, and antibodies to Apaf-1 are also provided.
Type:
Grant
Filed:
June 5, 1998
Date of Patent:
September 18, 2001
Assignees:
Board of Reports, The University of Texas System, Genentech, Inc.
Inventors:
Hua Zou, William J. Henzel, Xiaodong Wang