Patents Assigned to BOARD OF SUPERVISORS FOR THE UNIVERSITY OF LOUISIA
  • Isothiocyanatostilbenes as a novel method and product for treating cancer
    Patent number: 10980765
    Abstract: Products and methods for treating cancer in a human patient comprising administering to the patient therapeutically effective amount of a first pharmaceutically active agent, wherein the first pharmaceutically active agent is one of an isothiocyanatostilbene and a pharmacologically acceptable salt, solvate, ester, amide, clathrate, stereoisomer, enantiomer, prodrug or analog thereof, or a combination thereof.
    Type: Grant
    Filed: August 15, 2016
    Date of Patent: April 20, 2021
    Assignees: BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY, BOARD OF SUPERVISORS FOR THE UNIVERSITY OF LOUISIA
    Inventors: Alana Lea Gray, James Cardelli, David Thomas Coleman, Khalid El-Sayed, Mohamed M. Mohyeldin
  • Oleocanthal isolation and cancer treatment
    Patent number: 10945983
    Abstract: A method for extracting S (-)-Oleocanthal from olive oil comprising mixing a first volume of water with a second volume of olive oil to form an olive oil/water mixture; letting the olive oil/water mixture stand; removing an aqueous fraction from the olive oil/water mixture leaving a reduced S (-)-Oleocanthal containing olive oil; and filtering the aqueous fraction to create aqueous S (-)-Oleocanthal.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: March 16, 2021
    Assignee: BOARD OF SUPERVISORS FOR THE UNIVERSITY OF LOUISIA
    Inventors: Khalid A. El Sayed, Abu Bakar Siddique, Hassan Y. Ebrahim
  • Inhibitors of Metastasis, Methods of Generating Such Inhibitors and Their Therapeutic Applications
    Publication number: 20140286952
    Abstract: The chain of events that explains calcitonin receptor (CTR)-stimulated invasion and metastasis of prostate cancer cells was identified. The CTR-stimulated events depend on the interaction of CTR with the PDZ3 domain of ZO-1. Small peptides and small molecules were identified that inhibit this interaction. The small inhibitory peptides were synthesized and can be used to attenuate or inhibit metastasis in solid cancer tumors.
    Type: Application
    Filed: March 30, 2012
    Publication date: September 25, 2014
    Applicant: Board of Supervisors for the University of Louisia System, acting on behalf of the University of Lou
    Inventor: Girish V. Shah