Patents Assigned to BPSI Holdings, LLC
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Publication number: 20240024247Abstract: The present invention is directed film coating compositions for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which contain a water-soluble polymer, an opacifying agent such as, calcium carbonate or starch, and isomalt. The film coating compositions can be in the form of a fully formulated dry blend or as an aqueous suspension which can be applied either directly to a substrate or after the substrate has been coated with a subcoat. Oral substrates such as tablets coated with the film coating compositions are also disclosed and have high opacity and overall excellent appearance.Type: ApplicationFiled: January 10, 2022Publication date: January 25, 2024Applicant: BPSI HOLDINGS LLCInventors: Thomas MEHAFFEY, Manish GHIMIRE
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Patent number: 10758489Abstract: The present invention includes acidifying film coating compositions containing a polymer and an acidic component for use on orally-ingestible substrates such as tablets and the like. The acidifying coating compositions can be applied as an aqueous dispersion to an enteric-coated substrate to increase the disintegration resistance to aqueous media of up to pH 5.0. In preferred aspects, the acidic component is citric acid, lactic acid, stearic acid or mixtures thereof. Methods of preparing the dry film coatings, methods of preparing corresponding aqueous dispersions, methods of applying the coatings to substrates and the coated substrates themselves are also disclosed.Type: GrantFiled: March 29, 2019Date of Patent: September 1, 2020Assignee: BPSI HOLDINGS LLCInventors: Raxitkumar Y. Mehta, George Reyes, Jason Teckoe, Daniel To
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Publication number: 20190314286Abstract: The present invention includes acidifying film coating compositions containing a polymer and an acidic component for use on orally-ingestible substrates such as tablets and the like. The acidifying coating compositions can be applied as an aqueous dispersion to an enteric-coated substrate to increase the disintegration resistance to aqueous media of up to pH 5.0. In preferred aspects, the acidic component is citric acid, lactic acid, stearic acid or mixtures thereof. Methods of preparing the dry film coatings, methods of preparing corresponding aqueous dispersions, methods of applying the coatings to substrates and the coated substrates themselves are also disclosed.Type: ApplicationFiled: March 29, 2019Publication date: October 17, 2019Applicant: BPSI Holdings LLCInventors: Raxitkumar Y. Mehta, George Reyes, Jason Teckoe, Daniel To
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Patent number: 10232045Abstract: The present invention is directed to film coating compositions for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which contain a water-soluble polymer and guar gum. The film coating compositions can be applied either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the water-soluble polymer is a cellulosic or vinyl polymer. Aqueous suspensions containing the inventive film coating compositions and the coated substrates themselves are also disclosed. The resulting coated substrates have relatively low coefficients of static and dynamic friction on wet surfaces rendering them easier to swallow than prior art compositions.Type: GrantFiled: July 26, 2017Date of Patent: March 19, 2019Assignee: BPSI HOLDINGS LLCInventors: Jeffrey R. Gimbel, Daniel To, Jason Teckoe
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Patent number: 9789067Abstract: The present invention is directed to immediate release film coating compositions for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which contain medium chain glycerides as detackifiers. The film coating compositions can be applied either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the polymer is polyvinyl alcohol and the medium chain glycerides are mixtures of caprylic (8 carbon chain) and capric (10 carbon chain) mono- and diesters of glycerin. Aqueous suspensions comprising the inventive film coating compositions, methods of applying the coatings to substrates and the coated substrates themselves are also disclosed.Type: GrantFiled: October 24, 2016Date of Patent: October 17, 2017Assignee: BPSI Holdings, LLCInventors: Jason Teckoe, Bradley J. Prusak, Jeffrey R. Gimbel, Daniel To
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Patent number: 9504654Abstract: The present invention is directed to immediate release film coating compositions for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which contain medium chain glycerides as detackifiers. The film coating compositions can be applied either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the polymer is polyvinyl alcohol and the medium chain glycerides are mixtures of caprylic (8 carbon chain) and capric (10 carbon chain) mono- and diesters of glycerin. Aqueous suspensions comprising the inventive film coating compositions, methods of applying the coatings to substrates and the coated substrates themselves are also disclosed.Type: GrantFiled: January 14, 2015Date of Patent: November 29, 2016Assignee: BPSI HOLDINGS, LLCInventors: Jason Teckoe, Bradley J. Prusak, Jeffrey R. Gimbel, Daniel To
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Patent number: 9233074Abstract: The present invention includes pH dependent, dry film coating compositions containing calcium silicate for use on orally-ingestible substrates such as tablets and the like. The film coating compositions can be applied as an aqueous suspension either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the polymer is either an enteric or reverse-enteric polymer. Methods of preparing the dry film coatings, methods of preparing corresponding aqueous suspensions, methods of applying the coatings to substrates and the coated substrates themselves are also disclosed.Type: GrantFiled: February 25, 2014Date of Patent: January 12, 2016Assignee: BPSI HOLDINGS, LLCInventors: George Reyes, Charles R. Cunningham, Thomas P. Farrell, Cara Young
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Patent number: 9028862Abstract: The present invention is directed to immediate release film coating systems for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which have improved moisture barrier properties. The film coating systems can be applied either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the moisture barrier film coating is prepared as a dry powder mixture containing polyvinyl alcohol, a polymer with pH dependent solubility, a plasticizer, a glidant, and, optionally, a detackifier, an alkalizing agent and a pigment. Film coating compositions containing an aqueous suspension of the powder mixtures, methods of applying the coatings to substrates and the coated substrates are also disclosed.Type: GrantFiled: January 15, 2014Date of Patent: May 12, 2015Assignee: BPSI Holdings, LLCInventors: Thomas P. Farrell, Jason Teckoe
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Publication number: 20140248350Abstract: The present invention includes pH dependent, dry film coating compositions containing calcium silicate for use on orally-ingestible substrates such as tablets and the like. The film coating compositions can be applied as an aqueous suspension either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the polymer is either an enteric or reverse-enteric polymer. Methods of preparing the dry film coatings, methods of preparing corresponding aqueous suspensions, methods of applying the coatings to substrates and the coated substrates themselves are also disclosed.Type: ApplicationFiled: February 25, 2014Publication date: September 4, 2014Applicant: BPSI Holdings, LLC.Inventors: George REYES, Charles R. CUNNINGHAM, Thomas P. FARRELL, Cara YOUNG
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Publication number: 20140128477Abstract: The present invention is directed to immediate release film coating systems for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which have improved moisture barrier properties. The film coating systems can be applied either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the moisture barrier film coating is prepared as a dry powder mixture containing polyvinyl alcohol, a polymer with pH dependent solubility, a plasticizer, a glidant, and, optionally, a detackifier, an alkalizing agent and a pigment. Film coating compositions containing an aqueous suspension of the powder mixtures, methods of applying the coatings to substrates and the coated substrates are also disclosed.Type: ApplicationFiled: January 15, 2014Publication date: May 8, 2014Applicant: BPSI Holdings, LLC.Inventors: Thomas P. Farrell, Jason TECKOE
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Patent number: 8647645Abstract: The present invention is directed to immediate release film coating systems for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which have improved moisture barrier properties. The film coating systems can be applied either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the moisture barrier film coating is prepared as a dry powder mixture containing polyvinyl alcohol, a polymer with pH dependent solubility, a plasticizer, a glidant, and, optionally, a detackifier, an alkalizing agent and a pigment. Film coating compositions containing an aqueous suspension of the powder mixtures, methods of applying the coatings to substrates and the coated substrates are also disclosed.Type: GrantFiled: April 28, 2010Date of Patent: February 11, 2014Assignee: BPSI Holdings, LLCInventors: Thomas P. Farrell, Jason Teckoe
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Patent number: 8388983Abstract: The present invention is directed to film coating compositions for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which contain a fine particle size detackifier. The film coating compositions can be applied either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the polymer is either polyvinyl alcohol or a copolymer of polyvinyl alcohol. Aqueous suspensions comprising the inventive film coating compositions, methods of applying the coatings to substrates and the coated substrates themselves are also disclosed.Type: GrantFiled: April 28, 2010Date of Patent: March 5, 2013Assignee: BPSI Holdings, LLCInventors: Thomas P. Farrell, Jason Teckoe, Barry Friend, Scott Gulian
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Publication number: 20100303735Abstract: Methods and arrangements for forming a color gradient on a pharmaceutical dosage forms such as tablets are disclosed. In preferred aspects of the invention, a coating layer is applied to a tablet core so that the coating layer is different from the color of the tablet core. The coating layer is etched by one or more lasers to remove selected portions thereof and reveal the core. Removal of selected portions of the coating layer, while other portions remain unetched by the laser(s), causes a variation in the color of the coating layer. The color of the tablet core may be visible at locations at which portions of the coating layer have been entirely removed while the color of the coating layer, i.e., the color of any of the color coatings thereof, is visible at locations at which portions of the coating layer have been only partially removed or not removed at all.Type: ApplicationFiled: August 14, 2008Publication date: December 2, 2010Applicant: BPSI HOLDINGS, LLC.Inventors: Steven L. Yoder, Frederick R. Kettinger, Marc Dolbier
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Publication number: 20100291183Abstract: The present invention is directed to immediate release film coating systems for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which have improved moisture barrier properties. The film coating systems can be applied either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the moisture barrier film coating is prepared as a dry powder mixture containing polyvinyl alcohol, a polymer with pH dependent solubility, a plasticizer, a glidant, and, optionally, a detackifier, an alkalizing agent and a pigment. Film coating compositions containing an aqueous suspension of the powder mixtures, methods of applying the coatings to substrates and the coated substrates are also disclosed.Type: ApplicationFiled: April 28, 2010Publication date: November 18, 2010Applicant: BPSI HOLDINGS, LLC.Inventors: Thomas P. FARRELL, Jason TECKOE
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Publication number: 20100291159Abstract: The present invention is directed to film coating compositions for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which contain a fine particle size detackifier. The film coating compositions can be applied either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the polymer is either polyvinyl alcohol or a copolymer of polyvinyl alcohol. Aqueous suspensions comprising the inventive film coating compositions, methods of applying the coatings to substrates and the coated substrates themselves are also disclosed.Type: ApplicationFiled: April 28, 2010Publication date: November 18, 2010Applicant: BPSI HOLDINGS, LLC.Inventors: Thomas P. FARRELL, Jason TECKOE, Barry FRIEND, Scott GULIAN