Abstract: Immunoassay detection of bacterial diseases, bacteria, and microorganisms using a deionized water collection medium. The preferred enzyme immunoassay is of particular use in clinical or home testing application for detection of bacteria such as gonococcus, antigens derived from such bacteria, and antibodies against the bacteria. A colorimetric detection technique may be employed using chromogenic solutions containing tetramethylbenzidine or water soluble derivatives of tetramethylbenzidine.
Abstract: Colorimetric detection of bindable substances such as antibodies and antigens using chromogens of improved sensitivity and stability. The chromogens take the form of activated solutions containing tetramethylbenzidine or water soluble derivatives of tetramethylbenzidine. Such chromogens are of particular use in home testing applications for detection of antigens such as human chorionic gonadotropin, human luteinizing hormone, and gonococcus bacteria, as well as the detection of antibodies for these substances.
Type:
Grant
Filed:
August 20, 1982
Date of Patent:
March 5, 1985
Assignee:
BTC Diagnostics Limited Partnership
Inventors:
Bego Gerber, Elliott Block, Izak Bahar, Walter D. Cantarow, Mary Coseo, Cheryl Eaton, Wendy Jones, Patricia Kovac, John Bruins