Abstract: Increasing tolerance to butanol in yeast has been accomplished by increasing activity of the cell wall integrity pathway. Yeast with increased expression of SLT2p, a mitogen activated protein kinase of the MAPK module of the cell wall integrity pathway had increased tolerance to isobutanol. These yeast may be used for improved butanol production.
Type:
Application
Filed:
December 21, 2009
Publication date:
July 1, 2010
Applicant:
Butamax (TX) Advanced Biofuels LLC
Inventors:
MICHAEL G. BRAMUCCI, ROBERT A. LAROSSA, DANA R. SMULSKI