Patents Assigned to C A Casyso GmbH
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Patent number: 10955405Abstract: A platelet impedance measurement system including an electrode assembly allows for measurement of platelet function in blood. The assembly includes a substrate that acts as a substantially rigid base and includes an electrode. A portion of the electrode is exposed such that, when the electrode is placed in blood, the exposed portion is in contact with the blood for measuring impedance changes as platelets adhere to the electrode. Wires of the electrode can be attached to each end of the substrate and can run within a groove along a portion of the substrate. The substrate includes an open area where the wires in the groove exit and re-enter the substrate at the end of the substrate, allowing the wires to be exposed to the blood. The open area includes a brace, ensuring that the exposed wires are held in the appropriate placement relative to each other and to the cuvette.Type: GrantFiled: December 6, 2017Date of Patent: March 23, 2021Assignee: C A CASYSO GMBHInventors: Robert Hillman, Michael M. Gorin, Cory Lee McCluskey
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Patent number: 10830683Abstract: This disclosure provides a method for measuring coagulation of blood or plasma samples using viscoelastic tests (VET) wherein the measuring is performed in the presence of immobilised endothelial cells.Type: GrantFiled: December 5, 2017Date of Patent: November 10, 2020Assignee: C A Casyso GmbHInventors: Heinz Redl, Johannes Zipperle, Wolfgang Holnthoner, Christoph Schlimp, Herbert Schochl
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Patent number: 10746750Abstract: The present invention is directed to a cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, in particular a blood sample, comprising a cartridge body having at least one measurement cavity formed therein and having at least one probe element arranged in said at least one measurement cavity for performing a test on said sample liquid; and a cover being attachable on said cartridge body; wherein said cover covers at least partially said at least one measurement cavity and forms a retaining element for retaining said probe element in a predetermined position within said at least one measurement cavity. The invention is directed to a measurement system and a method for measuring viscoelastic characteristics of a sample liquid.Type: GrantFiled: September 28, 2018Date of Patent: August 18, 2020Assignee: C A Casyso GmbHInventors: Axel Schubert, Jose J. Romero-Galeano, Max Kessler
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Patent number: 10539579Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.Type: GrantFiled: December 3, 2015Date of Patent: January 21, 2020Assignee: C A CASYSO GMBHInventors: Michael Gorin, Robert S. Hillman, Cory Lee McCluskey, Hubert Martin Schwaiger
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Publication number: 20190353673Abstract: The present invention is directed to a cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, in particular a blood sample, comprising a cartridge body having at least one measurement cavity formed therein and having at least one probe element arranged in said at least one measurement cavity for performing a test on said sample liquid; and a cover being attachable on said cartridge body; wherein said cover covers at least partially said at least one measurement cavity and forms a retaining element for retaining said probe element in a predetermined position within said at least one measurement cavity. The invention is directed to a measurement system and a method for measuring viscoelastic characteristics of a sample liquid.Type: ApplicationFiled: July 23, 2019Publication date: November 21, 2019Applicant: C A Casyso GmbHInventors: Axel Schubert, Jose J. Romero-Galeano, Max Kessler
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Publication number: 20190353672Abstract: The present invention is directed to a cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, in particular a blood sample, comprising a cartridge body having at least one measurement cavity formed therein and having at least one probe element arranged in said at least one measurement cavity for performing a test on said sample liquid; and a cover being attachable on said cartridge body; wherein said cover covers at least partially said at least one measurement cavity and forms a retaining element for retaining said probe element in a predetermined position within said at least one measurement cavity. The invention is directed to a measurement system and a method for measuring viscoelastic characteristics of a sample liquid.Type: ApplicationFiled: July 23, 2019Publication date: November 21, 2019Applicant: C A Casyso GmbHInventors: Axel Schubert, Jose J. Romero-Galeano, Max Kessler
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Patent number: 10473674Abstract: Embodiments of a blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site. In some embodiments, the blood coagulation testing system includes a single-use cartridge component configured to measure and mix reagents with blood received from a blood sample reservoir. A mixing chamber in the single-use cartridge includes different reagent beads that, when exposed to a pre-determined volume of blood, dissolve and mix specific reagents with the blood. The assembled blood cartridge further includes configurations that are designed to prevent blood from prematurely mixing with reagent beads in the mixing chamber and to guide blood flow in the mixing chamber to dissolve reagent beads in a desired order. Thus, the mixture obtained from the mixing chamber can be readily utilized to generate results for the blood coagulation testing system.Type: GrantFiled: August 31, 2016Date of Patent: November 12, 2019Assignee: C A CASYSO GmbHInventors: Michael M. Gorin, Robert S. Hillman, Cory Lee McCluskey, Hubert Martin Schwaiger
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Publication number: 20190331699Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use components configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site. The systems can be configured with features such as individual actuation systems for each measurement module, and firmware for initial and ongoing calibration and error detection.Type: ApplicationFiled: May 10, 2019Publication date: October 31, 2019Applicant: C A Casyso GmbHInventors: Kevin Bels, Christian Brantl, Johannes Wittmann
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Publication number: 20190195898Abstract: The present invention is directed to a cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, in particular a blood sample, comprising a cartridge body having at least one measurement cavity formed therein and having at least one probe element arranged in said at least one measurement cavity for performing a test on said sample liquid; and a cover being attachable on said cartridge body; wherein said cover covers at least partially said at least one measurement cavity and forms a retaining element for retaining said probe element in a predetermined position within said at least one measurement cavity. The invention is directed to a measurement system and a method for measuring viscoelastic characteristics of a sample liquid.Type: ApplicationFiled: September 28, 2018Publication date: June 27, 2019Applicant: C A Casyso GmbHInventors: Axel Schubert, Jose J. Romero-Galeano, Max Kessler
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Patent number: 10295554Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use components configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site. The systems can be configured with features such as individual actuation systems for each measurement module, and firmware for initial and ongoing calibration and error detection.Type: GrantFiled: June 29, 2015Date of Patent: May 21, 2019Assignee: C A Casyso GmbHInventors: Kevin Bels, Christian Brantl, Johannes Wittmann
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Patent number: 10288630Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.Type: GrantFiled: December 3, 2015Date of Patent: May 14, 2019Assignee: C A Casyso GmbHInventors: Michael Gorin, Robert S. Hillman, Cory Lee McCluskey, Hubert Martin Schwaiger
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Publication number: 20180149664Abstract: The present invention is directed to a cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, in particular a blood sample, comprising a cartridge body having at least one measurement cavity formed therein and having at least one probe element arranged in said at least one measurement cavity for performing a test on said sample liquid; and a cover being attachable on said cartridge body; wherein said cover covers at least partially said at least one measurement cavity and forms a retaining element for retaining said probe element in a predetermined position within said at least one measurement cavity. The invention is directed to a measurement system and a method for measuring viscoelastic characteristics of a sample liquid.Type: ApplicationFiled: January 12, 2018Publication date: May 31, 2018Applicant: C A Casyso GmbHInventors: Axel Schubert, Jose J. Romero-Galeano, Max Kessler
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Patent number: 9897618Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.Type: GrantFiled: December 3, 2015Date of Patent: February 20, 2018Assignee: C A Casyso GmbHInventors: Michael Gorin, Robert S. Hillman, Cory Lee McCluskey, Hubert Martin Schwaiger
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Patent number: 9891209Abstract: A platelet impedance measurement system including an electrode assembly allows for measurement of platelet function in blood. The assembly includes a substrate that acts as a substantially rigid base and includes an electrode. A portion of the electrode is exposed such that, when the electrode is placed in blood, the exposed portion is in contact with the blood for measuring impedance changes as platelets adhere to the electrode. Wires of the electrode can be attached to each end of the substrate and can run within a groove along a portion of the substrate. The substrate includes an open area where the wires in the groove exit and re-enter the substrate at the end of the substrate, allowing the wires to be exposed to the blood. The open area includes a brace, ensuring that the exposed wires are held in the appropriate placement relative to each other and to the cuvette.Type: GrantFiled: September 24, 2015Date of Patent: February 13, 2018Assignee: C A Casyso GmbHInventors: Robert Hillman, Michael M. Gorin, Cory Lee McCluskey