Patents Assigned to Cabertech, Inc.
  • Functionalized calcium phosphate artificial bone and joint compositions and methods of use and manufacture
    Patent number: 10300167
    Abstract: The present invention provides a functionalized composition and resulting functionalized body or prosthesis for in vitro and in vivo use comprising at least one calcium phosphate containing phase that is functionalized with a linker group comprising at least one of an organic acid molecule, a phosphonic acid, an amine, N,N-dicyclohexylcarbodiimide, and 3-maleimidopropionic acid N-hydroxysuccinimide ester, and combinations thereof, and one or more of a chemical and/or a biologically active moieties, wherein the linker group provides for a reactive location for the attachment of the chemical or biologically active moiety, or both, to the calcium phosphate containing phase, and optionally including an unmodified and/or modified calcium aluminate containing phase. Methods of manufacturing a functionalized artificial prosthesis and methods of repairing a bone, vertebrae, or tissue structures are provided.
    Type: Grant
    Filed: July 28, 2011
    Date of Patent: May 28, 2019
    Assignees: CAberTech, Inc., Duquesne University of the Holy Spirit
    Inventors: Kenneth A. McGowan, Ellen S. Gawalt, Rachelle Palchesko
  • Artificial bone and joint compositions and methods of use and manufacture
    Patent number: 8778822
    Abstract: The present invention provides a ceramic porous body for in-vitro and in-vivo use comprising a composition comprising a calcium aluminate (CA) containing phase and optionally at least one of an accelerator, a retarder, a surfactant, a foaming agent, a reactive alumina, water, a fiber, and a biologically active material, and combinations thereof. Ceramic compositions are provides as well as method of using the ceramic compositions and methods of manufacturing a ceramic porous body. The ceramic porous bodies of this invention may be used as artificial bones, joints, in-vitro support structures, and in-vivo support structures for cells, tissues, organs, and nerve growth and regeneration.
    Type: Grant
    Filed: August 9, 2010
    Date of Patent: July 15, 2014
    Assignee: Cabertech, Inc.
    Inventor: Kenneth A. McGowan
  • Artificial bone and joint compositions and methods of use and manufacture
    Patent number: 8147993
    Abstract: The present invention provides a ceramic porous body for in-vitro and in-vivo use comprising a composition comprising a calcium aluminate (CA) containing phase and optionally at least one of an accelerator, a retarder, a surfactant, a foaming agent, a reactive alumina, water, a fiber, and a biologically active material, and combinations thereof. Ceramic compositions are provides as well as method of using the ceramic compositions and methods of manufacturing a ceramic porous body. The ceramic porous bodies of this invention may be used as artificial bones, joints, in-vitro support structures, and in-vivo support structures for cells, tissues, organs, and nerve growth and regeneration.
    Type: Grant
    Filed: May 29, 2007
    Date of Patent: April 3, 2012
    Assignee: Cabertech, Inc.
    Inventor: Kenneth A. McGowan