Abstract: The present invention provides methods for detecting the presence of antibodies to a microorganism (e.g., Chlamydia trachomatis) associated with a sexually transmitted disease in a biological sample, preferably urine. The methods of the invention comprise contacting the sample with an antigen from the microorganism and detecting the formation of an antigen-antibody complex.
Type:
Grant
Filed:
June 27, 1994
Date of Patent:
May 14, 1996
Assignee:
Calypte, Inc.
Inventors:
Howard B. Urnovitz, Toby D. Gottfried, David J. Robison
Abstract: The present invention provides a test strip for detecting, in a sample from a human subject, the presence of an antigenic substance which comprises a solid support, an antibody directed against the antigenic substance bound to a first discrete area on the solid support, an anti-human antibody bound to a second discrete area on the solid support as a positive control, and an antibody directed against an antigen which does not naturally occur in human subjects bound to a third discrete area on the solid support as a negative control. The present invention also provides a test strip for detecting, in a sample from a human subject, the presence of an antibody which comprises a solid support, an antigenic substance bound to a first discrete area on the solid support, an anti-human antibody bound to a second discrete area on the solid support as a positive control, and a negative control bound to a third discrete area on the solid support.