Abstract: The compositions and methods relate to an organic polymer-inorganic particle sensor material for detecting analytes. Interactions between the polymer and the particles are affected by the presence of analyte, which displaces the polymer and increases its free volume. This change in free volume can be detected, e.g., using an embedded piezoresistive microcantilever (EPM) sensor. Analytes that can be detected include noxious substances, such as hydrogen cyanide gas and carbon monoxide.

Abstract: Devices, methods and systems effective to evaluate a physical or chemical property of an ion exchange resin-treated biological fluid sample are provided.

Abstract: Devices, methods and systems effective to evaluate a physical or chemical property of a surfactant-treated biological fluid sample are provided.

Abstract: A device is disclosed which is a highly sensitive and selective sensor. The device is comprised of a sensor material secured into a fixed position on substrate, a deformable arm and a signaling component which creates a detectable signal in response to movement of the arm. The sensitivity of the device is enhanced by using a sensor material which undergoes a dramatic change in volume which may be accompanied by a phase change in response contact with a target such a molecule of interest. The selectivity of the device is enhanced by incorporating highly specific binding receptors (e.g. antibodies) into the sensor material which receptors bind to specific targets (e.g. peptide epitopes). The binding of the target molecule to the receptor causes the sensor material to change dramatically in volume thereby moving the arm causing the signaling component (e.g. a piezoresistor) to create a detectable signal (e.g. change in resistance) thereby indicating the present of the target.