Patents Assigned to Carafe Drug Innovation, LLC
  • Substituted 5-hydroxyoxindoles and their use as analgesics and fever reducers
    Patent number: 10537552
    Abstract: The present invention provides compounds and compositions which are useful in methods for modulating pain and fevers in a subject. These compounds are of the structure of formula (I), wherein Rx-R4, X, Y, and Z are defined herein, or a pharmaceutically acceptable salt, solvate, or prodrug thereof to the subject. In one embodiment, the compound is 5-hydroxy-7-methyloxindole.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: January 21, 2020
    Assignee: Carafe Drug Innovation, LLC
    Inventors: John R. Carson, Robert B. Raffa, Kenneth G. Carson