Patents Assigned to Cardiff Protides Limited
  • Phosphoramidate compounds and methods of use
    Patent number: 7951787
    Abstract: Phosphoramidate derivatives of nucleotides and their use in the treatment of cancer are described. The base moieties of, for example, each of deoxyuridine, cytarabine, gemcitabine and citidine may be substituted at the 5-position. The phosphoramidate moiety has attached to the P atom an aryl-O moiety and an ?-amino acid moiety. The ?-amino acid moiety may correspond to or be derived from either a naturally occurring or a non-naturally occurring amino acid.
    Type: Grant
    Filed: July 20, 2004
    Date of Patent: May 31, 2011
    Assignee: Cardiff Protides Limited
    Inventor: Christopher McGuigan