Abstract: A system and computer-implemented method for improving the quality of images, such as images used in medical diagnosis. In a first technique, sinogram data, intermediate volumes, and transmission CT-based attenuation correction files are created. Scatter correction is performed, and a scatter correction map is created. Misregistration offsets are measured, and a correction registration mask is created using volume reprojection. The two masks are combined and applied to create the enhanced image data. In a second technique, a difference may be determined for each parent and child pixel pair, and an average difference may be determined for all pairs. For each pair which is under the average difference, the child may be eliminated and replaced with a new child. This process may be iteratively repeated, with the image data being incrementally enhanced with each iteration. For both techniques, the enhanced image data may be communicated to an interpretive application for display.

Abstract: A method and apparatus for correcting scattering in SPECT I-123 imaging. The method generally includes: accessing list mode data for a plurality of pixels corresponding to a first SPECT I-123 image generated using a gamma camera; generating a raw energy spectrum for at least some of the pixels utilizing the acquired list mode data; acquiring a gamma camera model corresponding to the gamma camera; utilizing the gamma camera model and an iterative algorithm to apply a first scattering correction to the raw energy spectrum; utilizing a Compton window to apply a second scattering correction to the raw energy spectrum; and generating a correction table with the corrected raw energy spectrum.

Abstract: A method and apparatus for correcting scattering in SPECT I-123 imaging. The method generally includes: accessing list mode data for a plurality of pixels corresponding to a first SPECT I-123 image generated using a gamma camera; generating a raw energy spectrum for at least some of the pixels utilizing the acquired list mode data; acquiring a gamma camera model corresponding to the gamma camera; utilizing the gamma camera model and an iterative algorithm to apply a first scattering correction to the raw energy spectrum; utilizing a Compton window to apply a second scattering correction to the raw energy spectrum; and generating a correction table with the corrected raw energy spectrum.

Abstract: Embodiments of the present invention provide a computer program, method, and system to facilitate hybrid CT attenuation correction. In one embodiment, the method generally includes acquiring data from a scanner, utilizing an ordered subset expectation maximization-bayesian algorithm to reconstruct the acquired data, and forward projecting the reconstructed data. Such a configuration minimizes the computing resources required for reconstruction and improves attenuation correction accuracy.

Abstract: Embodiments of the present invention provide a computer program, method, and system to facilitate hybrid CT attenuation correction. In one embodiment, the method generally includes acquiring data from a scanner, utilizing an ordered subset expectation maximization-bayesian algorithm to reconstruct the acquired data, and forward projecting the reconstructed data. Such a configuration minimizes the computing resources required for reconstruction and improves attenuation correction accuracy.