Abstract: The present invention relates to a connection arrangement and a method of assembly, for providing a substantially tamper resistant connection with at least a first medical device. The connection arrangement (1) having a centre axis (A), the connection arrangement (1) comprises; a first connection member (21,161,521,621) for connection to the first medical device by means of a rotational motion in a first direction, and a body (60,120, 504, 603). Additionally the first connection member (21,161,521,621) and the body (60,120, 504, 603) are connected directly or indirectly together via at least one designated ruptureable retaining member (41, 141, 541, 641), the designated ruptureable retaining member (41, 141, 541, 641) is arranged to rupture at a predetermined breaking force, wherein the first connection member (21,161,521,621), and thereby the first medical device after assembly, can be displaced with respect to the body (60,120, 504, 603) after rupture.

Abstract: The present invention relates to a piercing member protection device (9) which comprises a first, a second and a third cylindrical member (100, 200, 300). The first cylindrical member (100) is at least partly encompassed by the second cylindrical member (200), and the second cylindrical member (200) is at least partly encompassed by the third cylindrical member (300). The third cylindrical member (300) comprises a piercing member (400) having a piercing tip (401). A first locking arrangement (250) is arranged to enable or prevent the turning of the first and third cylindrical member, with respect to the second cylindrical member, while a second locking arrangement (350) is arranged to enable or prevent movement of the piercing member (400) along the longitudinal centre axis A, so as to expose the piercing tip (401) of the piercing member (400). The piercing member protection device (9) provides a safe device which reduces the risk of accidental exposure of the piercing tip (401) and contamination for a user.

Abstract: The invention concerns a piercing member protection device, a kit of a piercing member protection device, a first and second fluid container and a method a method for transferring a fluid between a first and a second container using a piercing member protection device. The piercing member protection device comprises a protection chamber to protect at least the tip of a piercing member. The piercing member protection device further comprises a first and a second member arranged to each other.

Abstract: A first aspect of the invention relates to a method for aseptic preparation with an injection syringe. The syringe comprises a container for injection agent and an immovable connection nozzle connected to the container. The method entails charging the container with air. According to the invention air is forced to pass through an air filter arranged on the connection nozzle. This enables the syringe container to be charged with aseptic air in a simple and reliable fashion. Other aspects of the invention relate to devices for performing the method, viz. an injection syringe equipped with an air filter in the connection nozzle, a filter unit (2) connectable to an injection syringe's (1) connection nozzle (13) and a system comprising an injection syringe (1) and a separate filter unit (2). The invention devices convey advantages of the same kind as the invention method.

Abstract: A fluid transfer assembly comprising a bottle connector and a drug bottle. The bottle has a neck with an opening covered by a closure, while the connector has a hollow needle for penetrating the closure when establishing a fluid transfer line in the fluid transfer assembly. The assembly further comprises a neck element having locking members for irreversible coupling to the neck and to the connector. The neck element and the connector further comprise interacting guiding members for directing the hollow needle to penetrate the closure at a predetermined angle when establishing the fluid transfer line.

Abstract: A fluid transfer assembly, drug container, and method for enabling fluid transfer in an infusion system is taught. The assembly includes a fluid container containing an infusion fluid, and a drug container. The fluid container has at least one inlet port for receiving a medical substance from the drug container. The assembly further includes at least one fluid barrier controlling fluid passage between the drug container and the fluid container. The inlet port exhibits a first luer-lock connector, and the drug container is sealed by a cap exhibiting a second luer-lock connector for attachment to the first luer-lock connector. The fluid barrier is designed and arranged to be ruptured by an external force to allow the fluid passage.

Abstract: An infusion bag exhibiting an internal space which is surrounded by flexible walls, at least one outlet channel arranged through one of the walls for communication with the interior of the infusion bag, a communicating member integrated with the walls of the infusion bag which exhibits an opening accessible from the exterior of the infusion bag and an inlet channel which connects the opening with the interior of the infusion bag. An infusion system includes the infusion bag and a connecting member.

Abstract: Device for administrating a toxic fluid, comprising an infusion device for connection to an infusion bag. The infusion device is provided with an insertion portion for connecting the bag, and an infusion chamber for dosing a fluid flow via a flow duct in the insertion portion from the bag to an outlet arranged on the chamber. The insertion portion also comprises a ventilating duct which extends between the bag and the outside of the infusion device and ends in a connection arranged on the side of the infusion device for supplying fluid to be administrated. The connection is provided with at least one membrane which is air tight and penetrable by an injection needle.

Abstract: An infusion bag exhibiting an internal space which is surrounded by flexible walls, at least one outlet channel arranged through one of said walls for communication with the interior of the infusion bag, and a communicating member integrated with the walls of the infusion bag which exhibits an opening accessible from the exterior of the infusion bag, an inlet channel which connects said opening with the interior of the infusion bag. An infusion system comprising such an infusion bag and a connecting member.

Abstract: Device for administrating a toxic fluid, comprising an infusion device for connection to an infusion bag. The infusion device is provided with an insertion portion for connecting the bag, and an infusion chamber for dosing a fluid flow via a flow duct in the insertion portion from the bag to an outlet arranged on the chamber. The insertion portion also comprises a ventilating duct which extends between the bag and the outside of the infusion device and ends in a connection arranged on the side of the infusion device for supplying fluid to be administrated. The connection is provided with at least one membrane which is air tight and penetrable by an injection needle.

Abstract: A coupling device for coupling a vial connector to a drug vial, comprising actuating means (112′), for bringing the drug vial and/or the vial connector (105′) into a third position in which a cannula (108′) penetrates a seal (104′) of the drug vial in a direction along an axis (A) substantially perpendicular (&agr;≈90°) to a main plane (P) of the seal (104′), and guiding means (113) controlling the direction. The actuating means (112′) are designed for applying a force on the drug vial and/or the vial connector (105′) enabling the locking means (106′, 107′) to become permanently locked around the neck (102′). The first positioning means (110′) are adjustable for holding drug vials (101′) of several different dimensions and/or the second positioning means (111′) are adjustable for holding vial connectors (105′) of several different dimensions.