Patents Assigned to Cascade Medical Enterprises LLC
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Patent number: 8802362Abstract: Methods and devices for preparing a solid-fibrin web are provided. One method may include drawing blood from a patient, separating plasma from the blood, contacting the plasma with a calcium-coagulation activator and concurrently coagulating and axially centrifuging the plasma to form the solid-fibrin web. The solid-fibrin web may be suitable for regenerating body tissue in a living organism. Devices used in the methods may also be provided.Type: GrantFiled: May 18, 2010Date of Patent: August 12, 2014Assignee: Cascade Medical Enterprises, LLCInventors: Nicholas A. Grippi, Roberto C. Beretta
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Publication number: 20130299407Abstract: The invention provides a system for preparing an autologous solid-fibrin web suitable for regenerating tissue in a living organism. The system includes a sealed primary container containing a separation medium and a low-density high-viscosity liquid. The separation medium is capable of separating red blood cells from plasma when the container contains blood and is centrifuged, and the primary container has a first pressure. The system further includes a sealed secondary container containing a calcium-coagulation activator. The secondary container has a second pressure that is less than the first pressure. The system also includes a transfer device having a cannula with a first end and a second end. The first and second ends are adapted to puncture the sealed primary and secondary containers in order to provide fluid communication between the first and second containers.Type: ApplicationFiled: July 22, 2013Publication date: November 14, 2013Applicant: CASCADE MEDICAL ENTERPRISES, LLCInventors: Roberto Beretta, Nicholas A. Grippi
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Patent number: 8491564Abstract: The invention provides a system for preparing an autologous solid-fibrin web suitable for regenerating tissue in a living organism. The system includes a sealed primary container containing a separation medium and a low-density high-viscosity liquid. The separation medium is capable of separating red blood cells from plasma when the container contains blood and is centrifuged, and the primary container has a first pressure. The system further includes a sealed secondary container containing a calcium-coagulation activator. The secondary container has a second pressure that is less than the first pressure. The system also includes a transfer device having a cannula with a first end and a second end. The first and second ends are adapted to puncture the sealed primary and secondary containers in order to provide fluid communication between the first and second containers.Type: GrantFiled: April 15, 2009Date of Patent: July 23, 2013Assignee: Cascade Medical Enterprises, LLCInventors: Roberto Beretta, Nicholas A. Grippi
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Publication number: 20120156278Abstract: A method of regenerating tissue in a living organism. The method includes the act of contacting an affected area of the living organism with a solid-fibrin web, the solid-fibrin web comprising platelets that release growth factors about one minute after contact to regenerate the tissue in the living organism.Type: ApplicationFiled: December 19, 2011Publication date: June 21, 2012Applicant: Cascade Medical Enterprises, LLCInventors: Roberto Beretta, Nicholas A. Grippi
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Patent number: 7745106Abstract: Methods and devices for preparing a solid-fibrin web are provided. One method may include drawing blood from a patient, separating plasma from the blood, contacting the plasma with a calcium-coagulation activator and concurrently coagulating and axially centrifuging the plasma to form the solid-fibrin web. The solid-fibrin web may be suitable for regenerating body tissue in a living organism. Devices used in the methods may also be provided.Type: GrantFiled: June 26, 2003Date of Patent: June 29, 2010Assignee: Cascade Medical Enterprises, LLCInventors: Roberto C. Beretta, Nicholas A. Grippi
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Publication number: 20090258056Abstract: A method of regenerating tissue in a living organism. The method includes the act of contacting an affected area of the living organism with a solid-fibrin web, the solid-fibrin web comprising platelets that release growth factors about one minute after contact to regenerate the tissue in the living organism.Type: ApplicationFiled: April 14, 2009Publication date: October 15, 2009Applicant: CASCADE MEDICAL ENTERPRISES, LLCInventors: Roberto Beretta, Nicholas A. Grippi
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Publication number: 20090203613Abstract: The invention provides a system for preparing an autologous solid-fibrin web suitable for regenerating tissue in a living organism. The system includes a sealed primary container containing a separation medium and a low-density high-viscosity liquid. The separation medium is capable of separating red blood cells from plasma when the container contains blood and is centrifuged, and the primary container has a first pressure. The system further includes a sealed secondary container containing a calcium-coagulation activator. The secondary container has a second pressure that is less than the first pressure. The system also includes a transfer device having a cannula with a first end and a second end. The first and second ends are adapted to puncture the sealed primary and secondary containers in order to provide fluid communication between the first and second containers.Type: ApplicationFiled: April 15, 2009Publication date: August 13, 2009Applicant: CASCADE MEDICAL ENTERPRISES, LLCInventors: Roberto Beretta, Nicholas A. Grippi
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Publication number: 20080199513Abstract: A method of regenerating tissue in a living organism. The method includes the act of contacting an affected area of the living organism with a solid-fibrin web, the solid-fibrin web comprising platelets that release growth factors about one minute after contact to regenerate the tissue in the living organism.Type: ApplicationFiled: February 15, 2008Publication date: August 21, 2008Applicant: CASCADE MEDICAL ENTERPRISES, LLCInventors: Roberto Beretta, Nicholas A. Grippi
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Publication number: 20060074394Abstract: The invention provides a system for preparing an autologous solid-fibrin web suitable for regenerating tissue in a living organism. The system includes a sealed primary container containing a separation medium and a low-density high-viscosity liquid. The separation medium is capable of separating red blood cells from plasma when the container contains blood and is centrifuged, and the primary container has a first pressure. The system further includes a sealed secondary container containing a calcium-coagulation activator. The secondary container has a second pressure that is less than the first pressure. The system also comprises a transfer device including a cannula having a first end and a second end. The first and second ends are capable of puncturing the sealed primary and secondary containers in order to provide fluid communication between the first and second containers. The low-density high-viscosity liquid of the primary container is capable of blocking flow through the cannula upon entering therein.Type: ApplicationFiled: November 22, 2005Publication date: April 6, 2006Applicants: Cascade Medical Enterprises, LLC, Roberto BerettaInventors: Roberto Beretta, Nicholas Grippi
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Patent number: 6979307Abstract: The invention provides a system for preparing an autologous solid-fibrin web suitable for regenerating tissue in a living organism. The system includes a sealed primary container containing a separation medium and a low-density high-viscosity liquid. The separation medium separates red blood cells from plasma when the container contains blood and is centrifuged, and the primary container has a first pressure. The system further includes a sealed secondary container containing a calcium-coagulation activator. The secondary container has a second pressure that is less than the first pressure. The system also comprises a transfer device including a cannula having a first end and a second end. The first and second ends puncture the sealed primary and secondary containers in order to provide fluid communication between the first and second containers. The low-density high-viscosity liquid of the primary container blocks flow through the cannula upon entering therein.Type: GrantFiled: January 15, 2002Date of Patent: December 27, 2005Assignees: Cascade Medical Enterprises LLCInventors: Roberto Beretta, Nicholas A. Grippi