Patents Assigned to CDx Laboratories, Inc.
  • Computerized detection of laryngopharyngeal reflux
    Patent number: 9068975
    Abstract: A method and apparatus for determining a likelihood of LPR by analyzing a laryngeal cell preparation. The laryngeal sample is fixed on a microscope slide and analyzed by a microscope combined with an image acquisition system and a computer having an image recognition system. The image recognition system detects mobile cells that are implicated in the body's inflammatory response and counts how many of such cells are on the slide. The computer generates an absolute number of such cells and percentage values for such cells out the total number of mobile cells classified. The computer then utilizes the absolute numbers, the ratios of mobile cells with respect to each other—or a combination of both to generate a score. The score represents a probabilistic determination of inflammation.
    Type: Grant
    Filed: August 6, 2013
    Date of Patent: June 30, 2015
    Assignee: CDx Laboratories, Inc.
    Inventors: Mark Rutenberg, Stephen Frist
  • Feature dependent extended depth of focusing on semi-transparent biological specimens
    Patent number: 8199997
    Abstract: A method and system for constructing a digital image of a three-dimensional biological specimen that displays diagnostically important information—substantially to the exclusion of unimportant information. The system de-enhances features in a cellular specimen which are not diagnostically important and enhances those which are. The system selects the sharpest pixel for each pixel location from among a stack of image slices and copies them into a composite image.
    Type: Grant
    Filed: August 18, 2008
    Date of Patent: June 12, 2012
    Assignee: CDX Laboratories, Inc.
    Inventors: Mark Rutenberg, Richard Scott, Robert Tjon, Stephen Frist
  • Retractable brush for use with endoscope for brush biopsy
    Patent number: 7004913
    Abstract: A retractable brush structure is attached to a cylindrical rigid rod which in the closed position passes through a channel in an endoscope. After the brush passes through the endoscope, the brush moves against the tissue in order to remove cells from an area under examination. The brush is withdrawn from the endoscope and sample tissue is removed from said brush for examination after it is withdrawn from the endoscope.
    Type: Grant
    Filed: January 12, 2004
    Date of Patent: February 28, 2006
    Assignee: CDx Laboratories, Inc.
    Inventors: Mark Rutenberg, Stephen Frist
  • Retractable brush for use with endoscope for brush biopsy
    Patent number: 6676609
    Abstract: A retractable brush structure is attached to a cylindrical rigid rod which in the closed position passes through a channel in an endoscope. After the brush passes through the endoscope, the brush moves against the tissue in order to remove cells from an area under examination. The brush is withdrawn from the endoscope and sample tissue is removed from said brush for examination after it is withdrawn from the endoscope.
    Type: Grant
    Filed: December 17, 2002
    Date of Patent: January 13, 2004
    Assignee: CDx Laboratories, Inc.
    Inventors: Mark Rutenberg, Stephen Frist