Patents Assigned to Cellect Biotherapeutics Ltd.
  • Patent number: 11578306
    Abstract: Provided are methods for propagating mesenchymal stem cells (MSC), and particularly adipose derived stem cells, including incubating isolated cells obtained from a tissue or organ including MSC in a growth medium including an apoptosis inducing agent, under specified conditions. Further provided is an isolated cell population and kits for performing the methods.
    Type: Grant
    Filed: September 22, 2016
    Date of Patent: February 14, 2023
    Assignee: CELLECT BIOTHERAPEUTICS LTD.
    Inventors: Tal Almog, Shai Yarkoni
  • Publication number: 20210322474
    Abstract: Provided are methods for producing a population of cells enriched with non-activated/non-mature cells, in particular non-activated/non-mature T and/or B cells, optionally genetically modified T and/or B cells. The method includes contacting a heterogeneous population of mammalian cells with an apoptosis inducing ligand, wherein said contacting induces apoptosis of active/mature cells while non active/mature cells remain resistant to the apoptotic signal. Further provided are therapeutic uses of the enriched cell populations.
    Type: Application
    Filed: August 22, 2019
    Publication date: October 21, 2021
    Applicant: CELLECT BIOTHERAPEUTICS LTD.
    Inventors: Shai YARKONI, Hilit LEVI-BARZANI
  • Publication number: 20180340144
    Abstract: Provided are methods for propagating mesenchymal stem cells (MSC), and particularly adipose derived stem cells, including incubating isolated cells obtained from a tissue or organ including MSC in a growth medium including an apoptosis inducing agent, under specified conditions. Further provided is an isolated cell population and kits for performing the methods.
    Type: Application
    Filed: September 22, 2016
    Publication date: November 29, 2018
    Applicant: CELLECT BIOTHERAPEUTICS LTD.
    Inventors: Tal ALMOG, Shai YARKONI
  • Patent number: 9783778
    Abstract: The description discloses a device and a kit adapted for selection of cells that are resistant to receptor-mediated apoptosis and a method for using the device and kit. The device enables negative selection of mature immune cells which induce graft versus host disease (GvHD) out of a heterogeneous cell population which is introduced into the device. The device enables an efficient cell selection in simplified and cheaper setting by an off the shelf product—a solution that currently do not exist. The description further discloses uses for the device.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: October 10, 2017
    Assignee: Cellect Biotherapeutics Ltd.
    Inventors: Shai Yarkoni, Nadir Askenasy
  • Patent number: 9624469
    Abstract: An isolated immune regulatory cell having an exogenous cell death-inducing moiety attached to a surface thereof is disclosed herein. Additionally, a molecule comprising a cell death-inducing moiety heterologously attached to an immune regulatory cell-specific binding moiety is disclosed herein. Methods of generating and using same as well as pharmaceutical compositions comprising same are also disclosed.
    Type: Grant
    Filed: July 21, 2011
    Date of Patent: April 18, 2017
    Assignee: Cellect Biotherapeutics Ltd.
    Inventors: Shai Yarkoni, Nadir Askenasy