Patents Assigned to Celmatix, Inc.
  • Patent number: 10580516
    Abstract: The present invention generally relates to systems and methods for determining the probability of a pregnancy at a selected point in time. Systems and methods of the invention employ an algorithm that has been trained on a reference set of data from a plurality of women for whom at least one of fertility-associated phenotypic traits, fertility-associated medical interventions, or pregnancy outcomes are known, in which the algorithm accounts for any woman who ceases pregnancy attempts prior to reaching a live birth outcome.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: March 3, 2020
    Assignee: CELMATIX, INC.
    Inventors: Michael Elashoff, Hrishikesh Karvir, Piraye Yurttas Beim
  • Patent number: 10339267
    Abstract: The present invention generally relates to systems and methods for determining the probability of a pregnancy at a selected point in time. Systems and methods of the invention employ an algorithm that has been trained on a reference set of data from a plurality of women for whom at least one of fertility-associated phenotypic traits, fertility-associated medical interventions, or pregnancy outcomes are known, in which the algorithm accounts for any woman who ceases pregnancy attempts prior to reaching a live birth outcome.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: July 2, 2019
    Assignee: CELMATIX, INC.
    Inventors: Michael Elashoff, Hrishikesh Karvir, Piraye Yurttas Beim
  • Patent number: 10208350
    Abstract: Methods for assessing infertility and related pathologies and informing treatment type and timing thereof are provided. According to certain embodiments, methods of the invention include determining levels of one or more transcripts present in a sample obtained from a subject suspected of having endometriosis, identifying transcript levels that correspond to a regulation pattern specific to a time-point in a uterine cycle, and characterizing endometriosis of the subject based upon the identified transcript levels. The invention includes methods for assessing age-associated increase in aneuploidy rates based on FSH levels and IVF success rates based on obesity in PCOS patients.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: February 19, 2019
    Assignee: Celmatix Inc.
    Inventors: Piraye Yurttas Beim, David Emlyn Parfitt, Michael Elashoff
  • Patent number: 10162800
    Abstract: The present invention generally relates to systems and methods for determining the probability of a pregnancy at a selected point in time. Systems and methods of the invention employ an algorithm that has been trained on a reference set of data from a plurality of women for whom at least one of fertility-associated phenotypic traits, fertility-associated medical interventions, or pregnancy outcomes are known, in which the algorithm accounts for any woman who ceases pregnancy attempts prior to reaching a live birth outcome.
    Type: Grant
    Filed: October 11, 2013
    Date of Patent: December 25, 2018
    Assignee: Celmatix Inc.
    Inventors: Michael Elashoff, Hrishikesh Karvir, Piraye Yurttas Beim
  • Patent number: 9836577
    Abstract: The invention generally relates to methods and devices for assessing risk of female infertility. In certain aspects, methods of the invention involve obtaining a sample, conducting an assay on at least one infertility-associated biomarker, and assessing risk to the patient of developing early-onset decrease in fertility based upon results of the assay.
    Type: Grant
    Filed: January 26, 2015
    Date of Patent: December 5, 2017
    Assignee: Celmatix, Inc.
    Inventors: Piraye Yurttas Beim, Michael Elashoff
  • Patent number: 9177098
    Abstract: The present invention generally relates to systems and methods for determining the probability of a pregnancy at a selected point in time. Systems and methods of the invention employ an algorithm that has been trained on a reference set of data from a plurality of women for whom at least one of fertility-associated phenotypic traits, fertility-associated medical interventions, or pregnancy outcomes are known, in which the algorithm accounts for any woman who ceases pregnancy attempts prior to reaching a live birth outcome.
    Type: Grant
    Filed: October 17, 2012
    Date of Patent: November 3, 2015
    Assignee: Celmatix Inc.
    Inventors: Michael Elashoff, Hrishikesh Karvir, Piraye Yurttas Beim
  • Publication number: 20140171337
    Abstract: The invention generally relates to methods and devices for assessing risk of female infertility. In certain aspects, methods of the invention involve obtaining a sample, conducting an assay on at least one infertility-associated biomarker, and assessing risk to the patient of developing early-onset decrease in fertility based upon results of the assay.
    Type: Application
    Filed: December 16, 2013
    Publication date: June 19, 2014
    Applicant: Celmatix, Inc.
    Inventor: Piraye Yurttas Beim
  • Publication number: 20140107934
    Abstract: The present invention generally relates to systems and methods for determining the probability of a pregnancy at a selected point in time. Systems and methods of the invention employ an algorithm that has been trained on a reference set of data from a plurality of women for whom at least one of fertility-associated phenotypic traits, fertility-associated medical interventions, or pregnancy outcomes are known, in which the algorithm accounts for any woman who ceases pregnancy attempts prior to reaching a live birth outcome.
    Type: Application
    Filed: October 11, 2013
    Publication date: April 17, 2014
    Applicant: CELMATIX, INC.
    Inventors: Michael Elashoff, Hrishikesh Karvir, Piraye Yurttas Beim
  • Publication number: 20120094845
    Abstract: The invention generally relates to methods and devices for assessing infertility. In certain embodiments, methods of the invention involve conducting an assay to determine presence or absence of a mutation in a plurality of genes selected from Table 1, and assessing infertility based on results of the assay, wherein presence of a mutation in at least two of the genes from Table 1 is indicative of infertility.
    Type: Application
    Filed: October 14, 2011
    Publication date: April 19, 2012
    Applicant: CELMATIX, INC.
    Inventors: Piraye Yurttas, Laura Bandak
  • Publication number: 20110071033
    Abstract: The invention generally relates to methods and devices for assessing infertility. In certain embodiments, methods of the invention involve conducting an assay to determine presence or absence of a mutation in a plurality of genes selected from Table 1, and assessing infertility based on results of the assay, wherein presence of a mutation in at least two of the genes from Table 1 is indicative of infertility.
    Type: Application
    Filed: September 23, 2010
    Publication date: March 24, 2011
    Applicant: Celmatix, Inc.
    Inventors: Piraye Yurttas, Laura Bandak