Patents Assigned to CENTRE EUROPEEN D'ETUDE DU DIABETE
  • DECORIN FOR ITS USE IN THE TREATMENT OF DIABETES
    Publication number: 20220072106
    Abstract: The disclosure relates to decorin or a composition containing decorin for use in the treatment of type 1 diabetes (particularly in the context of transplanting pancreatic islet cells), type 2 diabetes or gestational diabetes.
    Type: Application
    Filed: December 19, 2019
    Publication date: March 10, 2022
    Applicant: CENTRE EUROPEEN D'ETUDE DU DIABETE
    Inventors: Karim BOUZAKRI, Michel PINGET
  • Functionalized membrane for a chamber for encapsulating cells producing at least one substance of therapeutic interest and bioartificial organ comprising such a membrane
    Patent number: 9005960
    Abstract: The present invention relates to a functionalized semi-permeable membrane composed of a porous biocompatible support pretreated so as to increase the surface energy thereof and characterized in that it includes at least two layers, each having a hydrophilic polymer and at least one biological active molecule, and to the use thereof in particular for producing a bioartificial organ.
    Type: Grant
    Filed: May 31, 2011
    Date of Patent: April 14, 2015
    Assignees: Association pour les Transferts de Technologie du Mans, Centre Europeen d'Etude du Diabete
    Inventors: Gilbert Legeay, Séverine Sigrist, Arnaud Coudreuse
  • VECTOR FOR ORAL ADMINISTRATION
    Publication number: 20140120161
    Abstract: A vector for the oral administration of at least one pharmacologically active substance enabling the active substance to move from the intestinal lumen to the blood, optionally via interstitial liquid, without any substantial degradation of the substance, includes an essentially hydrophilic matrix having an outer surface which is modified by one or several chemical species providing the vector with an essentially lipophilic quality and containing one or several active substances. The vector is associated with a gastroresistant vehicle enabling it to pass into the stomach without any denaturation and/or degradation of the active substance. The invention also relates to pharmaceutical compositions containing the vector. The vectors can be used to produce medicaments used in human or veterinary medicine.
    Type: Application
    Filed: December 24, 2013
    Publication date: May 1, 2014
    Applicants: CENTRE EUROPEEN D'ETUDE DU DIABETE (30% PARTIAL INTEREST), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
    Inventors: YVES FRERE, LOUIS DANICHER, ALAIN BELCOURT
  • Functionalized Membrane For A Chamber For Encapsulating Cells Producing At Least One Substance Of Therapeutic Interest And Bioartificial Organ Comprising Such A Membrane
    Publication number: 20130131828
    Abstract: The present invention relates to a functionalized semi-permeable membrane composed of a porous biocompatible support pretreated so as to increase the surface energy thereof and characterized in that it comprises at least two layers, each comprising a hydrophilic polymer and at least one biologically active molecule, and to the use thereof in particular for producing a bioartificial organ.
    Type: Application
    Filed: May 31, 2011
    Publication date: May 23, 2013
    Applicants: Association Pour Les Transferts De Technologie Du Mans, CENTRE EUROPEEN D'ETUDE DU DIABETE
    Inventors: Gilbert Legeay, Séverine Sigrist, Arnaud Coudreuse
  • membrane for encapsulation chamber of cells producing at least a biologically active substance and bioartificial organ comprising same
    Patent number: 7056726
    Abstract: The invention concerns a semipermeable chamber for encapsulation of cells producing at least a biological substance of interest, characterised in that it consists of a porous polycarbonate biocompatible film modified at the surface by generated polar sites and covered with at least a layer of hydrophilic polymer.
    Type: Grant
    Filed: January 29, 2002
    Date of Patent: June 6, 2006
    Assignees: Association pour les Transferts de Technologies du Mans, Universite Catholique de louvain, Centre Europeen d'Etude du Diabete (CEED)
    Inventors: Gilbert Legeay, Patrick Bertrand, Alain Belcourt, Laurence Kessler