Patents Assigned to CENTRE HOSPITALIER UNIVERSITAIRE DE NICE
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Publication number: 20220351847Abstract: A computer-implemented method for determining a path of a patient in a hospital includes receiving administrative and/or subjective data of the patient; comparing said administrative and subjective data with administrative and subjective data of previously treated patient stored in a database to determine previously treated patients having a given level of similarity with the patient, wherein said database comprises, for each previously treated patient, a recorded path; collecting hospital resources availability data; and determining an initial path of the patient in the hospital wherein said initial path includes calculated probabilities of using specific hospital resources in a given sequence, based on the recorded path of said previously treated patients having said level of similarity with the patient, and said hospital resources availability data.Type: ApplicationFiled: September 16, 2020Publication date: November 3, 2022Applicant: CENTRE HOSPITALIER UNIVERSITAIRE DE NICEInventors: Hervé Haas, Antoine Tran
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Publication number: 20200264166Abstract: A process for isolating or extracting rare cells from a biological sample comprising filtering a biological sample, which may be treated or diluted, through a filter that has a pore size, pore density or other physical properties that retain rare cells, but which permits other kinds of cells to pass through the filter. This process also comprises multiple analyses performed on rare cells after their extraction or isolation by filtration to diagnostically identify the presence of rare cells in a biological sample and to use their diagnostic identification and molecular characterization for diagnostic purposes such as for early diagnosis of diseases, namely for early diagnosis of cancer and to select, guide, monitor treatments and in particular to select targeted treatments and to monitor the response and/or resistance to them.Type: ApplicationFiled: January 17, 2020Publication date: August 20, 2020Applicants: RARECELLS SAS, UNIVERSITE DE NICE SOPHIA ANTIPOLIS, CENTRE HOSPITALIER UNIVERSITAIRE DE NICE, UNIVERSITE PARIS DESCARTES, Assistance Publique-Hopitaux de Paris (AP-HP), Institut National de la Sante et de la Recherche Medicale (Inserm)Inventors: Patrizia PATERLINI-BRECHOT, Paul HOFMAN, Sophie Marie Genevieve LAGET, Thierry CAPIOD
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Patent number: 9561304Abstract: The invention relates to a biomaterial containing coagulated blood or coagulated bone marrow aspirate and biphasic calcium phosphate ceramic particles, to a production method thereof and to the use of same for the production of an implant that enables bone tissue regeneration.Type: GrantFiled: June 22, 2009Date of Patent: February 7, 2017Assignees: Centre National de la Recherche Scientifique, Centre Hospitalier Universitaire De NiceInventors: Thierry Balaguer, Nathalie Rochet, Christophe Trojani, Florian Boukhechba, Georges Carle
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Patent number: 9421227Abstract: The invention relates to a biomaterial containing calcium phosphate, in particular hydroxyapatite or a material containing hydroxyapatite, such as biphasic calcium phosphates and calcium phosphate cements, and to the use thereof for the production of an implant or for fitting a prosthesis for the purpose of bone tissue regeneration.Type: GrantFiled: June 21, 2013Date of Patent: August 23, 2016Assignees: Centre National de la Recherche Scientifique, Centre Hospitalier Universitaire de NiceInventors: Thierry Balaguer, Nathalie Rochet, Georges Carle
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Patent number: 9233124Abstract: The invention relates to a biomaterial containing calcium phosphate, in particular hydroxyapatite or a material containing hydroxyapatite, such as biphasic calcium phosphates and calcium phosphate cements, and to the use thereof for the production of an implant or for fitting a prosthesis for the purpose of bone tissue regeneration.Type: GrantFiled: June 22, 2009Date of Patent: January 12, 2016Assignees: Centre National de la Recherche Scientifique, Centre Hospitalier Universitaire De NiceInventors: Thierry Balaguer, Nathalie Rochet, Georges Carle
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Publication number: 20150094217Abstract: The invention relates to an in vitro analysis method for predicting resistance to azacitidine treatment in a patient, using the BCL2L10 protein contained in a sample of biological fluid taken from said patient, and also biological molecules which specifically bind the BCL2L10 protein. It is characterized in that a sample of biological fluid is recovered from a patient; the percentage of total cells in said biological fluid expressing the BCL2L10 protein is calculated; this calculated percentage is compared with a reference threshold value, this threshold value being between 20% and 60%; and resistance to azacitidine treatment is diagnosed in a patient who has a percentage of cells expressing the BCL2L10 protein in said biological fluid which is greater than said reference value.Type: ApplicationFiled: February 28, 2013Publication date: April 2, 2015Applicants: UNIVERSITÉ NICE SOPHIA ANTIPOLIS, CENTRE HOSPITALIER UNIVERSITAIRE DE NICEInventors: Thomas Cluzeau, Patrick Auberger, Guillaume Robert, Frédéric Luciano
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Patent number: 8895520Abstract: A method of treatment of a human patient suffering from myeloid neoplasias, includes administrating a therapeutically effective amount of 5-aminoimidazole-4-carboxamide (acadesine), acadesine precursors or acadesine derivatives.Type: GrantFiled: October 26, 2011Date of Patent: November 25, 2014Assignees: Universite Nice Sophia Antipolis, Centre Hospitalier Universitaire de Nice, INSERM (Institut National de la Sante et de la Recherche Medicale)Inventors: Thomas Cluzeau, Patrick Auberger, Guillaume Robert
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Publication number: 20140155904Abstract: The invention relates to a biomaterial containing calcium phosphate, in particular hydroxyapatite or a material containing hydroxyapatite, such as biphasic calcium phosphates and calcium phosphate cements, and to the use thereof for the production of an implant or for fitting a prosthesis for the purpose of bone tissue regeneration.Type: ApplicationFiled: June 21, 2013Publication date: June 5, 2014Applicants: Centre Hospitalier Universitaire de Nice, Center National de la Recherche ScientifiqueInventors: Thierry Balaguer, Nathalie Rochet, Georges Carle
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Publication number: 20130109648Abstract: The invention relates to a method of treatment of a human patient suffering from Myeloid Neoplasias, comprising administrating a therapeutically effective amount of acadesine, acadesine precursors or acadesine derivatives.Type: ApplicationFiled: October 26, 2011Publication date: May 2, 2013Applicants: Universite Nice Sophia Antipolis, INSERM (Institut National de la Sante et de la Recherche Medicale), Centre Hospitalier Universitaire de NiceInventors: Thomas Cluzeau, Patrick Auberger, Guillaume Robert
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Publication number: 20110182950Abstract: The invention relates to a biomaterial containing coagulated blood or coagulated bone marrow aspirate and biphasic calcium phosphate ceramic particles, to a production method thereof and to the use of same for the production of an implant that enables bone tissue regeneration.Type: ApplicationFiled: June 22, 2009Publication date: July 28, 2011Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRE HOSPITALIER UNIVERSITAIRE DE NICEInventors: Thierry Balaguer, Nathalie Rochet, Christophe Trojani, Florian Boukhechba, Georges Carle
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Publication number: 20110178525Abstract: The invention relates to a biomaterial containing calcium phosphate, in particular hydroxyapatite or a material containing hydroxyapatite, such as biphasic calcium phosphates and calcium phosphate cements, and to the use thereof for the production of an implant or for fitting a prosthesis for the purpose of bone tissue regeneration.Type: ApplicationFiled: June 22, 2009Publication date: July 21, 2011Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRE HOSPITALIER UNIVERSITAIRE DE NICEInventors: Thierry Balaguer, Nathalie Rochet, Georges Carle