Patents Assigned to CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES
  • Publication number: 20240110828
    Abstract: A method for determining the operating state of a light-emitting implant implanted in the brain of a living being, the light-emitting implant including a light source responsible for emitting light into the brain of the living being, the method using a diagnosing device that includes a receiver of a light signal transmitted through a first eye of the living being and a device for determining the operating state of the light-emitting implant based on the received transmitted light signal.
    Type: Application
    Filed: September 28, 2023
    Publication date: April 4, 2024
    Applicants: Commissariat à l'Energie Atomique et aux Energies Alternatives, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES, UNIVERSITE GRENOBLE ALPES
    Inventors: Pierre BLEUET, Claude CHABROL, Cécile MORO, Stephan CHABARDES, Alim Louis BENABID
  • Publication number: 20230346727
    Abstract: A compound of general formula (III?), or one of its pharmaceutically acceptable salts, for its use for the treatment of hemophilia in a subject, in particular for the restoration of coagulation in the plasma of a subject suffering from hemophilia, this compound being advantageously administered by oral route:
    Type: Application
    Filed: July 23, 2021
    Publication date: November 2, 2023
    Applicants: UNIVERSITE GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES, INSTITUT POLYTECHNIQUE DE GRENOBLE
    Inventors: Aline THOMAS, Marie-Claire DAGHER, Muriel JOURDAN, Romain NAVARRO, Benoît POLACK, Raphaël MARLU, Landry SEYVE, Renaud ZELLI
  • Patent number: 11660314
    Abstract: A device intended to be implanted in a human or animal body, in order to produce hydrogen in situ from molecules present in the body medium in which the device is implanted, this device having an anode and a cathode, which are each electrically connected to a pole of an electrical energy source, and having a semi-permeable material separating the electrodes from the body medium, in which device, when the connection to the electrical energy source is effective in situ, in the presence of body fluid, a closed electrical circuit is formed, with production of hydrogen at the cathode, the semi-permeable material having a cutoff threshold of between 50 and 500 Da.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: May 30, 2023
    Assignees: UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Philippe Cinquin, Abdelkader Zebda, Jean-Pierre Alcaraz, Donald Keith Martin
  • Patent number: 11464670
    Abstract: The invention relates to a device for cooling an organ locally, that includes an elongate stem including a far end intended to make contact with an organ to be cooled and comprising including a cooling element having a cold finger, a crystal that has a capacity to cool via excitation at a set excitation wavelength, said crystal being positioned adjacent to said cooling element, an optical guide that is able to convey a light signal at said excitation wavelength and that opens onto said crystal, and an illuminating system including at least one light source, which light source is arranged to emit said light signal.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: October 11, 2022
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES
    Inventors: Nicolas Aubert, Claude Chabrol, Stephan Chabardes, Laurent Duraffourg
  • Patent number: 11285305
    Abstract: The invention relates to an implantable device suitable for being fixed in a fixation position to a wall of a patient's stomach, the implantable device being accommodated in the stomach when the implantable device is in the fixation position, the implantable device being characterised in that it comprises a reserve of an active substance and an injector suitable for administering the active substance to the patient.
    Type: Grant
    Filed: December 7, 2017
    Date of Patent: March 29, 2022
    Assignees: UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES
    Inventors: Philippe Cinquin, Patrick Tuvignon
  • Publication number: 20210401618
    Abstract: A probe intended to be at least partially implanted in a living being, with a view to locally cooling at least one region of the living being, this probe notably including a cooling member present at its distal end, which member is intended to make contact with the region to be cooled, and a thermoelectric cooling module including a cold region making contact with the cooling member.
    Type: Application
    Filed: June 25, 2021
    Publication date: December 30, 2021
    Applicants: Commissariat à l'Energie Atomique et aux Energies Alternatives, UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES
    Inventors: Quentin BORNTRAGER, Claude CHABROL, Stephan CHABARDES
  • Publication number: 20210282963
    Abstract: The invention relates to a device for cooling an organ locally, that includes an elongate stem including a far end intended to make contact with an organ to be cooled and comprising including a cooling element having a cold finger, a crystal that has a capacity to cool via excitation at a set excitation wavelength, said crystal being positioned adjacent to said cooling element, an optical guide that is able to convey a light signal at said excitation wavelength and that opens onto said crystal, and an illuminating system including at least one light source, which light source is arranged to emit said light signal.
    Type: Application
    Filed: September 12, 2017
    Publication date: September 16, 2021
    Applicants: COMMISSARIAT A L'ENEGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES
    Inventors: Nicolas AUBERT, Claude CHARBROL, Stephan CHABARDES, Luarent DURAFFOURG
  • Patent number: 11045539
    Abstract: The present disclosure is related to a live-attenuated strain of Pseudomonas for its use as a vaccine, and for use in a method for preventive immunizing and for treating Pseudomonas infection, in particular in patients suffering from cystic fibrosis. Preferably, the live-attenuated strain of Pseudomonas is furthermore treated to become ‘killed but metabolically active’.
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: June 29, 2021
    Assignees: Universite Grenoble Alpes, Centre Hospitalier Universitaire Grenoble Alpes, Establissement Francais Du Sang
    Inventors: Audrey Le Gouellec, Bertrand Toussaint, Jean-Luc Lenormand, David Laurin, Elodie Meynet
  • Patent number: 10590191
    Abstract: The invention relates to anti-Tau nanobodies.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: March 17, 2020
    Assignees: UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Daniel Fagret, Marcelle Moulin, Catherine Ghezzi, Pascale Perret, Sabine Chierici
  • Publication number: 20200023052
    Abstract: The present disclosure is related to a live-attenuated strain of Pseudomonas for its use as a vaccine, and for use in a method for preventive immunizing and for treating Pseudomonas infection, in particular in patients suffering from cystic fibrosis. Preferably, the live-attenuated strain of Pseudomonas is furthermore treated to become ‘killed but metabolically active’.
    Type: Application
    Filed: February 15, 2018
    Publication date: January 23, 2020
    Applicants: UNIVERSITÉ GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES, ETABLISSEMENT FRANÇAIS DU SANG
    Inventors: Audrey LE GOUELLEC, Bertrand TOUSSAINT, Jean-Luc LENORMAND, David LAURIN, Elodie MAYNET
  • Patent number: 10426519
    Abstract: A minimally invasive system for dynamic correction of a spinal deformity in patients includes: a flat ligament made of synthetic material, a plurality of staples intended to be anchored on a respective vertebral body of the patient to hold the ligament against each vertebral body, and a device for mechanically tensioning the ligament.
    Type: Grant
    Filed: April 13, 2016
    Date of Patent: October 1, 2019
    Assignees: Universite Grenoble Alpes, Centre Hospitalier Universitaire Grenoble Alpes
    Inventors: Aurélien Courvoisier, Ahmad Eid, Jacques Griffet
  • Patent number: 10106858
    Abstract: Disclosed is a method for the in vitro detection of strains of Legionella pneumophila, resistant to antibiotics, in particular to the fluoroquinolones. Also disclosed are nucleotide probes and a kit of reagents allowing the detection of Legionella pneumophila bacterial strains that are resistant to antibiotics, in particular of the fluoroquinolone type.
    Type: Grant
    Filed: June 17, 2014
    Date of Patent: October 23, 2018
    Assignees: UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES
    Inventors: Max Maurice Louis Maurin, Dominique Schneider, Lubana Shadoud, Sophie Jarraud, Jean Francois Timsit, Jerome Etienne
  • Publication number: 20170332986
    Abstract: Radiographic imaging system including: an x-ray transmission unit; an x-ray receiver unit; a plate made from a material opaque to x-rays and situated between the transmission unit and the receiver unit, the plate including at least four channels, each channel enabling a part of the x-rays emitted by the transmission unit to pass through the channel; and an image processing unit configured to determine the coordinates of the projected patterns and to calculate a position of the receiver unit from the coordinates of the projected patterns and from the coordinates of the channels.
    Type: Application
    Filed: November 5, 2015
    Publication date: November 23, 2017
    Applicants: UNIVERSITÉ GRENOBLE ALPES, SURGIQUAL INSTITUTE, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES
    Inventors: Yannick GRONDIN, Philippe AUGERAT, Philippe CINQUIN, Laurent DESBAT, Benjamin SPENCER