Patents Assigned to CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES
-
Publication number: 20240110828Abstract: A method for determining the operating state of a light-emitting implant implanted in the brain of a living being, the light-emitting implant including a light source responsible for emitting light into the brain of the living being, the method using a diagnosing device that includes a receiver of a light signal transmitted through a first eye of the living being and a device for determining the operating state of the light-emitting implant based on the received transmitted light signal.Type: ApplicationFiled: September 28, 2023Publication date: April 4, 2024Applicants: Commissariat à l'Energie Atomique et aux Energies Alternatives, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES, UNIVERSITE GRENOBLE ALPESInventors: Pierre BLEUET, Claude CHABROL, Cécile MORO, Stephan CHABARDES, Alim Louis BENABID
-
Publication number: 20230346727Abstract: A compound of general formula (III?), or one of its pharmaceutically acceptable salts, for its use for the treatment of hemophilia in a subject, in particular for the restoration of coagulation in the plasma of a subject suffering from hemophilia, this compound being advantageously administered by oral route:Type: ApplicationFiled: July 23, 2021Publication date: November 2, 2023Applicants: UNIVERSITE GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES, INSTITUT POLYTECHNIQUE DE GRENOBLEInventors: Aline THOMAS, Marie-Claire DAGHER, Muriel JOURDAN, Romain NAVARRO, Benoît POLACK, Raphaël MARLU, Landry SEYVE, Renaud ZELLI
-
Patent number: 11660314Abstract: A device intended to be implanted in a human or animal body, in order to produce hydrogen in situ from molecules present in the body medium in which the device is implanted, this device having an anode and a cathode, which are each electrically connected to a pole of an electrical energy source, and having a semi-permeable material separating the electrodes from the body medium, in which device, when the connection to the electrical energy source is effective in situ, in the presence of body fluid, a closed electrical circuit is formed, with production of hydrogen at the cathode, the semi-permeable material having a cutoff threshold of between 50 and 500 Da.Type: GrantFiled: December 21, 2018Date of Patent: May 30, 2023Assignees: UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)Inventors: Philippe Cinquin, Abdelkader Zebda, Jean-Pierre Alcaraz, Donald Keith Martin
-
Patent number: 11464670Abstract: The invention relates to a device for cooling an organ locally, that includes an elongate stem including a far end intended to make contact with an organ to be cooled and comprising including a cooling element having a cold finger, a crystal that has a capacity to cool via excitation at a set excitation wavelength, said crystal being positioned adjacent to said cooling element, an optical guide that is able to convey a light signal at said excitation wavelength and that opens onto said crystal, and an illuminating system including at least one light source, which light source is arranged to emit said light signal.Type: GrantFiled: September 12, 2017Date of Patent: October 11, 2022Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPESInventors: Nicolas Aubert, Claude Chabrol, Stephan Chabardes, Laurent Duraffourg
-
Patent number: 11285305Abstract: The invention relates to an implantable device suitable for being fixed in a fixation position to a wall of a patient's stomach, the implantable device being accommodated in the stomach when the implantable device is in the fixation position, the implantable device being characterised in that it comprises a reserve of an active substance and an injector suitable for administering the active substance to the patient.Type: GrantFiled: December 7, 2017Date of Patent: March 29, 2022Assignees: UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPESInventors: Philippe Cinquin, Patrick Tuvignon
-
Publication number: 20210401618Abstract: A probe intended to be at least partially implanted in a living being, with a view to locally cooling at least one region of the living being, this probe notably including a cooling member present at its distal end, which member is intended to make contact with the region to be cooled, and a thermoelectric cooling module including a cold region making contact with the cooling member.Type: ApplicationFiled: June 25, 2021Publication date: December 30, 2021Applicants: Commissariat à l'Energie Atomique et aux Energies Alternatives, UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPESInventors: Quentin BORNTRAGER, Claude CHABROL, Stephan CHABARDES
-
Publication number: 20210282963Abstract: The invention relates to a device for cooling an organ locally, that includes an elongate stem including a far end intended to make contact with an organ to be cooled and comprising including a cooling element having a cold finger, a crystal that has a capacity to cool via excitation at a set excitation wavelength, said crystal being positioned adjacent to said cooling element, an optical guide that is able to convey a light signal at said excitation wavelength and that opens onto said crystal, and an illuminating system including at least one light source, which light source is arranged to emit said light signal.Type: ApplicationFiled: September 12, 2017Publication date: September 16, 2021Applicants: COMMISSARIAT A L'ENEGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPESInventors: Nicolas AUBERT, Claude CHARBROL, Stephan CHABARDES, Luarent DURAFFOURG
-
Patent number: 11045539Abstract: The present disclosure is related to a live-attenuated strain of Pseudomonas for its use as a vaccine, and for use in a method for preventive immunizing and for treating Pseudomonas infection, in particular in patients suffering from cystic fibrosis. Preferably, the live-attenuated strain of Pseudomonas is furthermore treated to become ‘killed but metabolically active’.Type: GrantFiled: February 15, 2018Date of Patent: June 29, 2021Assignees: Universite Grenoble Alpes, Centre Hospitalier Universitaire Grenoble Alpes, Establissement Francais Du SangInventors: Audrey Le Gouellec, Bertrand Toussaint, Jean-Luc Lenormand, David Laurin, Elodie Meynet
-
Patent number: 10590191Abstract: The invention relates to anti-Tau nanobodies.Type: GrantFiled: October 27, 2017Date of Patent: March 17, 2020Assignees: UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)Inventors: Daniel Fagret, Marcelle Moulin, Catherine Ghezzi, Pascale Perret, Sabine Chierici
-
Publication number: 20200023052Abstract: The present disclosure is related to a live-attenuated strain of Pseudomonas for its use as a vaccine, and for use in a method for preventive immunizing and for treating Pseudomonas infection, in particular in patients suffering from cystic fibrosis. Preferably, the live-attenuated strain of Pseudomonas is furthermore treated to become ‘killed but metabolically active’.Type: ApplicationFiled: February 15, 2018Publication date: January 23, 2020Applicants: UNIVERSITÉ GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES, ETABLISSEMENT FRANÇAIS DU SANGInventors: Audrey LE GOUELLEC, Bertrand TOUSSAINT, Jean-Luc LENORMAND, David LAURIN, Elodie MAYNET
-
Patent number: 10426519Abstract: A minimally invasive system for dynamic correction of a spinal deformity in patients includes: a flat ligament made of synthetic material, a plurality of staples intended to be anchored on a respective vertebral body of the patient to hold the ligament against each vertebral body, and a device for mechanically tensioning the ligament.Type: GrantFiled: April 13, 2016Date of Patent: October 1, 2019Assignees: Universite Grenoble Alpes, Centre Hospitalier Universitaire Grenoble AlpesInventors: Aurélien Courvoisier, Ahmad Eid, Jacques Griffet
-
Patent number: 10106858Abstract: Disclosed is a method for the in vitro detection of strains of Legionella pneumophila, resistant to antibiotics, in particular to the fluoroquinolones. Also disclosed are nucleotide probes and a kit of reagents allowing the detection of Legionella pneumophila bacterial strains that are resistant to antibiotics, in particular of the fluoroquinolone type.Type: GrantFiled: June 17, 2014Date of Patent: October 23, 2018Assignees: UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPESInventors: Max Maurice Louis Maurin, Dominique Schneider, Lubana Shadoud, Sophie Jarraud, Jean Francois Timsit, Jerome Etienne
-
Publication number: 20170332986Abstract: Radiographic imaging system including: an x-ray transmission unit; an x-ray receiver unit; a plate made from a material opaque to x-rays and situated between the transmission unit and the receiver unit, the plate including at least four channels, each channel enabling a part of the x-rays emitted by the transmission unit to pass through the channel; and an image processing unit configured to determine the coordinates of the projected patterns and to calculate a position of the receiver unit from the coordinates of the projected patterns and from the coordinates of the channels.Type: ApplicationFiled: November 5, 2015Publication date: November 23, 2017Applicants: UNIVERSITÉ GRENOBLE ALPES, SURGIQUAL INSTITUTE, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPESInventors: Yannick GRONDIN, Philippe AUGERAT, Philippe CINQUIN, Laurent DESBAT, Benjamin SPENCER