Abstract: The invention relates to a surgical device to be used in orthopaedic treatment. In particular, the present invention relates to a surgical system for minimally invasive treatment of a trigger finger.
Type:
Application
Filed:
February 16, 2022
Publication date:
April 25, 2024
Applicant:
Centre Hospitalier Universitaire Vaudois (CHUV)
Abstract: The present invention relates to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with interleukin 26 (IL-26), including inflammatory diseases, such as psoriasis and/or bacterial infections.
Type:
Grant
Filed:
July 13, 2016
Date of Patent:
August 25, 2020
Assignees:
CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS (CHUV), BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Inventors:
Michel Gilliet, Jeremy Di Domizio, Stephan Meller
Abstract: The present invention relates to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with interleukin 26 (IL-26), including inflammatory diseases, such as psoriasis and/or bacterial infections.
Type:
Application
Filed:
July 13, 2016
Publication date:
July 26, 2018
Applicants:
CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS (CHUV), BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Inventors:
Michel GILLIET, Jeremy DI DOMIZIO, Stephan MELLER
Abstract: A treatment of Huntington's disease (HD) using the Clustered-Regularly Interspaced Short Palindromic Repeats (CRISPR) system. This technology offers the possibility to design a small RNA (sgRNA), which is incorporated into a CRISPR-associated protein (Cas9) to recognize and induce DNA double-strand breaks at a specific target location. In the context of HD, this allows to block the expression of the mutant huntingtin or repair the CAG expansion causing the disease.
Type:
Application
Filed:
August 4, 2015
Publication date:
August 10, 2017
Applicant:
CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS (CHUV)
Abstract: The present invention relates to methods of in vitro preparation of a parental cell bank (PCB) from foetal tissue consisting of foetal epiphyseal tissue, foetal Achilles tendon tissue and foetal skin tissue, using a rapid mechanical primary cell culture selection of cell type to be used in methods for wound and tissue repair.
Type:
Grant
Filed:
February 12, 2015
Date of Patent:
September 6, 2016
Assignee:
CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS (CHUV)
Abstract: The present invention relates to micro-organisms and to methods of producing proteins. More specifically, the inventions relates to a host cell useful for the expression of heterozygous proteins in which the host cell, Pichia pastoris, has been genetically modified so that the gene for endogenous secreted subtilisin Sub2 protease is completely or partially inactivated.
Type:
Grant
Filed:
December 13, 2010
Date of Patent:
April 22, 2014
Assignee:
Centre Hospitalier Universitaire Vaudois (CHUV)
Abstract: The present invention relates to micro-organisms and to methods of producing proteins. More specifically, the inventions relates to a host cell useful for the expression of heterozygous proteins in which the host cell, Pichia pastoris, has been genetically modified so that the gene for endogenous secreted subtilisin Sub2 protease is completely or partially inactivated.
Type:
Application
Filed:
December 13, 2010
Publication date:
November 22, 2012
Applicant:
CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS (CHUV)
Abstract: The present invention relates to a novel enzyme composition comprising a prolyl protease and tripeptidyl proteases having unique catalytic properties. The present invention further relates to methods for producing the enzyme composition as well as a pharmaceutical composition and a food supplement containing the enzyme composition and its use in the degradation of polypeptides.
Type:
Application
Filed:
December 20, 2010
Publication date:
November 1, 2012
Applicant:
CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS (CHUV)