Patents Assigned to Centro de Ingenienia Genetica y Biotecnologia
  • Four branched dendrimer-PEG for conjugation to proteins and peptides
    Patent number: 8703893
    Abstract: A polymeric dendrimer-like structure with four branches of monomethoxy-polyethylene glycol that can be represented as: The carboxylic group of the previous structure can be functionalized for the production of conjugates of pharmaceutical interest. The binding of this dendrimer-like polyethylene glycol to therapeutic proteins improves their in vitro and in vivo stability.
    Type: Grant
    Filed: November 20, 2006
    Date of Patent: April 22, 2014
    Assignee: Centro de Ingenienia Genetica y Biotecnologia
    Inventors: José Ángel Ramón Hernández, Fidel Raúl Castro Odio, Vivian-María Sáez Martinez, Rolando Páez Meircles, Eduardo Fernández Sánchez