Abstract: Improved stability and high activity of certain compositions containing as essential ingredients the vitamins thiamine, riboflavin and niacin and an edible yeast which are useful in counteracting the toxic and intoxicating effects of alcohol consumption, is obtained by incorporating the vitamins, together with a vegetable gum, in a yeast cream, followed by dehydration under controlled temperature conditions. The dehydrated yeast compositions may be mixed with selected non-reactive diluents (excipients) and tableted without the use of added binders to provide a stable composition in tablet form.