Abstract: The invention relates to methods for determining the sequence of a genomic region of interest comprising a target nucleotide sequence comprising, fragmenting a crosslinked DNA, ligating the fragmented cross linked DNA, reversing the crosslinking and determining at least part of the sequences of ligated DNA fragments which comprise a target nucleotide sequence.
Type:
Application
Filed:
July 8, 2011
Publication date:
July 18, 2013
Applicant:
Cergentis B.V.
Inventors:
Wouter Leonard de Laat, Max Jan van Min