Abstract: The present invention is concerned with new pyridine double esters of formula (I), their acids, and pharmaceutically acceptable salts. These compounds can be obtained by oxydation of the corresponding 1,4-dihydropyridines, and they are useful as cardioprotective agents in pharmaceutical compositions.

Abstract: The preparation of esters of 1,4-dihydropyridine, useful in the prevention and treatment of cardiovascular disorders such as atheroma, of the formula ##STR1## wherein X is a phenyl moiety and Y is piperazine, piperidine or an amide of a benzenecarboxylic acid, is described.

Abstract: New esters of 1,4-dihydropyridine (and their salts) are prepared which are useful as pharmacologically active ingredients in particular in medicaments for the preventive and curative treatment of cardiovascular disorders.Said esters have for formula ##STR1## where R, R.sub.1, R.sub.2, R.sub.3, R.sub.4, X and Y and index n are defined as in claim 1.

Abstract: New glycerol 1,2-bis-aminoalkyl ethers corresponding to the formula ##STR1## and their salts, in which R.sup.1 represents a C.sub.1-3 alkyl, C.sub.1-3 alkoxy, trifluoromethyl group or a halogen, R.sup.2 represents hydrogen, a halogen, a C.sub.1-3 alkyl, C.sub.1-3 alkoxy group, and R.sup.3 represents a C.sub.1-3 alkyl group, having local anesthetic and anti-arrhythmic properties.

Abstract: Compounds of the formula: ##EQU1## wherein X represents a carbonyl group C=O or a methylene group --CH.sub.2 --,R represents a phenyl, mono- or di-halophenyl or 2-pyridyl group,R.sub.1 represents a pyridyl or C.sub.3.sub.-7 -cycloalkyl group,R.sub.2 represents hydrogen, hydroxy or a C.sub.1.sub.-5 -alkyl group,R.sub.3 represents 1 to 3 groups which can be hydrogen, halogen, C.sub.1.sub.-3 -alkyl, methoxy or dioxymethylene,Q represents the (CH.sub.2).sub.n group, n having the value 0, 1, 2, 3, the --CH=CH--CH.sub.2 -- or --O--CH.sub.2 --CH.sub.2 -- group,Have analgesic, hypothermic and anti-depressant properties, accompanied by a weak psycholeptic action, anticonvulsive and slightly sedative properties, vasodilatory, spasmolytic, anti-bronchiospastic, anti-histaminic, anti-allergical, anti-emetical properties, and which increase the cerebral and myocardic bloodrate and -oxygenation.