Abstract: The present invention relates to a method and composition for the aspiration, processing, testing and infusion of bone marrow derived stem cells, as an adjuvant treatment in cardiovascular disorders. More specifically, the invention provides for the methods and compositions for the aspiration, analysis, processing, infusate preparation and infusion of bone-marrow derived stem cells, particularly in a rapid point-of-care environment, wherein a centrifugal fractionation and optically monitored separation of the bone marrow yield desired cellular product in the desired concentration and viscosity.
Type:
Grant
Filed:
June 4, 2014
Date of Patent:
September 13, 2016
Assignee:
CESCA THERAPEUTICS, INC.
Inventors:
Kenneth Harris, Dalip Sethi, Venkatesh Ponemone, Gary R. Cohan
Abstract: The present invention relates to a method and composition for the aspiration, processing, testing and infusion of bone marrow derived stem cells, as an adjuvant treatment in cardiovascular disorders. More specifically, the invention provides for the methods and compositions for the aspiration, analysis, processing, infusate preparation and infusion of bone-marrow derived stem cells, particularly in a rapid point-of-care environment, wherein a centrifugal fractionation and optically monitored separation of the bone marrow yield desired cellular product in the desired concentration and viscosity.
Type:
Grant
Filed:
June 5, 2014
Date of Patent:
August 2, 2016
Assignee:
Cesca Therapeutics, Inc.
Inventors:
Kenneth Harris, Dalip Sethi, Venkatesh Ponemone, Gary R. Cohan
Abstract: The present invention relates to a method and composition for the aspiration, processing, testing and infusion of bone marrow derived stem cells, as an adjuvant treatment in cardiovascular disorders. More specifically, the invention provides for the methods and compositions for the aspiration, analysis, processing, infusate preparation and infusion of bone-marrow derived stem cells, particularly in a rapid point-of-care environment, wherein a centrifugal fractionation and optically monitored separation of the bone marrow yield desired cellular product in the desired concentration and viscosity.
Type:
Grant
Filed:
June 5, 2014
Date of Patent:
July 19, 2016
Assignee:
Cesca Therapeutics, Inc.
Inventors:
Kenneth Harris, Dalip Sethi, Venkatesh Ponemone, Gary R. Cohan
Abstract: A device for separating and isolating components of a biological fluid comprising a container for containing the fluid to be processed, a tube cap assembly for dosing the container while providing filling and extraction communication therewith, a float assembly disposed within the container for funneling and controlling biological fluid flow into an inverted domed shaped isolation chamber within the float and controlling the biological fluid flow out of the isolation chamber for effecting an encapsulation or a sealed isolation of at least one component or fraction of the biological fluid flow within the isolation chamber during a centrifugation process. The device further comprising a flexible tube for connecting an extraction passageway disposed within the float assembly and an extraction valve of the tube cap assembly for allowing extraction of at least the one component or fraction encapsulated or isolated within the chamber.
Type:
Grant
Filed:
August 16, 2013
Date of Patent:
June 28, 2016
Assignee:
Cesca Therapeutics, Inc.
Inventors:
John R. Chapman, Vijay Kumar, Brian K. Cinquini, Phillip D. Kingsley