Patents Assigned to Challenge Bioproducts Co., Ltd.
  • Chemical modification of biomedical materials with genipin
    Patent number: 6608040
    Abstract: Biocompatible cross-linked materials, suitable for use in implants, wound dressings, and blood substitutes, are described. The materials are prepared by cross-linking biological substances, such as collagen, chitosan, or hemoglobin, with genipin, a naturally occurring cross-linking agent. The cross-linking agent has much lower toxicity than conventionally used reagents, and the cross-linked products have good thermal and mechanical stability as well as biocompatibility.
    Type: Grant
    Filed: September 27, 2001
    Date of Patent: August 19, 2003
    Assignee: Challenge Bioproducts Co., Ltd.
    Inventors: Ching-Kuan Lin, Thomas Chau-Jen Lee, Hsing-Wen Sung