Abstract: Disclosed is an air cushion shoe with various kinds of air chambers capable of absorbing the shocks generated by the application of the weight of a wearer in a vertical direction and distributing the absorbed shocks in a horizontal direction. The air cushion shoe of this invention has an upper and a sole, including a group of air chambers protrudedly exposed on the bottom surface of the sole of the shoe, the group of air chambers having a single air chamber that is located on the heel portion of the sole and divided into a first single air chamber and a second single air chamber by means of a partition and having plural kinds of communicating air chambers that are located on the whole portion except the heel portion of the sole, wherein the single air chamber is separated from the plural kinds of communicating air chambers.