Abstract: Disclosed herein are light diffuser devices comprising a sphere having at least two openings, a track, a light source, a cart, and one or more plates, and their methods of use. Also, disclosed here are light diffuser systems comprising a light diffuser device and a portable infrared gas analyzer.
Type:
Grant
Filed:
August 11, 2021
Date of Patent:
April 23, 2024
Assignee:
Chapman University
Inventors:
Z. Carter Berry, Gregory R. Goldsmith, Fernando Silva
Abstract: This disclosure relates to microcapsule particles for targeted delivery of drugs. In certain embodiments, the particles comprise polyelectrolyte polymers, e.g., layers of anionic polymers and cationic polymers. In certain embodiments, the particles have a fibrinogen coating. In certain embodiments, the particles contain a polysaccharide core and/or a polysaccharide coating encapsulating drugs, proteins, clotting agents, coagulation factors, or anticoagulants. In certain embodiments, this disclosure contemplates methods of using particles disclosed herein to prevent or reduce onset of or duration of bleeding. In certain embodiments, this disclosure contemplates methods of using particles disclosed herein to prevent or reduce onset of blood clotting.
Type:
Grant
Filed:
September 23, 2022
Date of Patent:
August 22, 2023
Assignees:
Emory University, Georgia Tech Research Corporation, Chapman University, Children's Healthcare of Atlanta, Inc.
Inventors:
Wilbur A. Lam, Caroline Hansen, Yumiko Sakurai, Andrew Lyon
Abstract: A rapid assay for determining the presence of bacteria in a sample, such as a contaminated food sample, is disclosed. The assay comprises contacting the sample with a bacteria-specific ligand associated with a substrate, wherein bacteria present in the sample bind the ligand; contacting the bound bacteria with a detection agent; detecting the presence of bacteria in the sample by measuring the quantity of detection agent associated with the sample.
Abstract: This disclosure relates to microcapsule particles for targeted delivery of drugs. In certain embodiments, the particles comprise polyelectrolyte polymers, e.g., layers of anionic polymers and cationic polymers. In certain embodiments, the particles have a fibrinogen coating. In certain embodiments, the particles contain a polysaccharide core and/or a polysaccharide coating encapsulating drugs, proteins, clotting agents, coagulation factors, or anticoagulants. In certain embodiments, this disclosure contemplates methods of using particles disclosed herein to prevent or reduce onset of or duration of bleeding. In certain embodiments, this disclosure contemplates methods of using particles disclosed herein to prevent or reduce onset of blood clotting.
Type:
Grant
Filed:
January 31, 2017
Date of Patent:
October 11, 2022
Assignees:
Emory University, Children's Healthcare of Atlanta, Inc., Georgia Tech Research Corporation, Chapman University
Inventors:
Wilbur A. Lam, Caroline Hansen, Yumiko Sakurai, Andrew Lyon
Abstract: Disclosed herein are methods and compositions for administering immunotherapy to a subject in need thereof and for treating a subject in need thereof, where in the methods the subject is administered an effective amount of an inhibitor of nNOS for inducing an immunotherapeutic response in the subject and for treating the subject. The disclosed methods and composition may be utilized for treating a subject having a cell proliferative disease or disorder such as melanoma.
Type:
Grant
Filed:
December 4, 2019
Date of Patent:
September 13, 2022
Assignees:
Northwestern University, Chapman University
Abstract: Disclosed herein are methods and compositions for administering immunotherapy to a subject in need thereof and for treating a subject in need thereof, where in the methods the subject is administered an effective amount of an inhibitor of nNOS for inducing an immunotherapeutic response in the subject and for treating the subject. The disclosed methods and composition may be utilized for treating a subject having a cell proliferative disease or disorder such as melanoma.
Type:
Application
Filed:
December 4, 2019
Publication date:
June 11, 2020
Applicants:
Northwestern University, Chapman University