Abstract: Provided herein are hemoglobin-based therapeutic agents useful for treating cancer, pharmaceutical composition including the same, and methods of use and preparation thereof.
Type:
Grant
Filed:
July 20, 2020
Date of Patent:
February 14, 2023
Assignee:
Cheer Global Limited
Inventors:
Sui-Yi Kwok, Norman Fung-Man Wai, Lan Zou
Abstract: Provided herein is a method for treating an inflammatory bowel disease in a subject in need thereof, the method comprising administering a therapeutically effective amount of a hemoglobin to the subject.
Type:
Grant
Filed:
December 4, 2020
Date of Patent:
December 27, 2022
Assignee:
Cheer Global Limited
Inventors:
Sui Yi Kwok, Norman Fung Man Wai, Chi Shing Tai
Abstract: The present disclosure relates to recombinant hemoglobins with improved oxygen carrying capacity and methods of preparation and use thereof. The present disclosure also relates to a pharmaceutical composition including the recombinant hemoglobin useful for treating oxygen deficiency related diseases or conditions, such as stroke, hemorrhagic shock, peripheral arterial disease (PAD), acute mountain sickness (AMS), cancer, and Parkinson's disease (PD).
Type:
Grant
Filed:
January 31, 2020
Date of Patent:
August 25, 2020
Assignee:
Cheer Global Limited
Inventors:
Sui Yi Kwok, Norman Fung Man Wai, Shan Yu, Terence Shau Yin Wai