Patents Assigned to Chemsyn Science Laboratories
  • Process of preparing an isothiocyanate intermediate used in the preparation of xylazine
    Patent number: 5043442
    Abstract: A process for preparing 2,6-dimethylphenylisothiocyanate comprises the steps of dissolving 2,6-dimethylaniline in carbon disulfide and ammonium hydroxide to form a dithiocarbamate salt. The salt is reacted with ethyl chloroformate to form 2,6-dimethylphenylisothiocyanate, which may thereafter be reacted with 3-amino-1-propanol and subsequently cyclized, by treating with hydrochloric acid, to form xylazine.
    Type: Grant
    Filed: April 2, 1990
    Date of Patent: August 27, 1991
    Assignee: Chemsyn Science Laboratories
    Inventors: Paul Ruehle, Amy M. Bunker