Patents Assigned to CHENGUANG BIOTECH GROUP CO., LTD.
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Patent number: 11891411Abstract: An industrialization method for comprehensive utilization of Stevia rebaudiana. The major improvement is in that the Stevia rebaudiana is extracted by using a high-concentration alcohol solution, then the extracted solution is purified by using an organic solvent, and the pH of the extracted solution is adjusted to be alkaline according to the acidic characteristic of chlorogenic acid to enable the chlorogenic acid to be formed into a salt and have an increased polarity so as to achieve effective separation of the chlorogenic acid and a glucoside component in an adsorption process. The method allows the high-quality stevioside and chlorogenic acid to be obtained, significantly improves the comprehensive utilization rate of Stevia rebaudiana, reduces the waste of natural Stevia rebaudiana resources, reduces the resource consumption in a production process, reduces waste discharge, and is a high-benefit green production process.Type: GrantFiled: March 30, 2021Date of Patent: February 6, 2024Assignee: Chenguang Biotech Group Co., Ltd.Inventors: Meili Xu, Yunhe Lian, Hong Tian, Wei Gao, Yachao Xu
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Patent number: 11723879Abstract: The present invention discloses a method for preparing a lycopene micro-capsule powder, wherein lycopene is fully mixed with an aqueous phase to obtain a lycopene emulsion, and the emulsion is then ground to a particle size less than 1 ?m, and spray dried. The aqueous phase comprises: a gelatin enzymatic hydrolysate with a molecular weight of 5,000-10,000 Da, disaccharide, polysaccharide, and an antioxidant. The disaccharide is one or more of sucrose, maltose and lactose; and the polysaccharide is one or more of pullulan and chitosan.Type: GrantFiled: June 8, 2020Date of Patent: August 15, 2023Assignee: Chenguang Biotech Group Co., Ltd.Inventors: Wei Gao, Jianzhong Xu, Xiangyu Yang, Hong Tian, Yamei Li, Xinchao Jia
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Publication number: 20230219872Abstract: Disclosed is an industrial extraction method of cannabidiol, pertaining to the field of medicine and chemical industry. The present invention aims to resolve the problems of difficulty in wax removal, low extraction rate of cannabidiol, and excessively high content of tetrahydrocannabinol during extraction using conventional solvents in the prior art. The extraction method employs raw material pretreatment, granulation, extraction, liquid-liquid extraction, decolorization, concentration, and other processes, such that wax removal from an extracted liquid is improved, the purity of a crude cannabidiol oil can be increased to 60%, and 40% of tetrahydrocannabinol can be removed. The method has high extraction yields and low costs, and can be implemented in large-scale industrial production.Type: ApplicationFiled: May 27, 2021Publication date: July 13, 2023Applicant: CHENGUANG BIOTECH GROUP CO., LTD.Inventors: Qingguo LU, Yunhe LIAN, Wei Gao, Yang LI, Hong TIAN
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Patent number: 11549128Abstract: A pretreatment method for producing a raw material of lycopene, comprising: uniformly mixing tomato peel residue with a fermenting agent, an antioxidant and an enzyme preparation, and subjecting the resultant to light-proof anaerobic fermentation. The present invention employs bacteria-enzyme-combined fermentation technology, which prolongs the storage period of wet tomato peel residue, and also destroys the cell wall of tomato peels, thus facilitating exaction of lycopene and improving the purity of lycopene extracted in the later stage.Type: GrantFiled: October 25, 2017Date of Patent: January 10, 2023Assignee: CHENGUANG BIOTECH GROUP CO., LTD.Inventors: Qingguo Lu, Wenjie Han, Zhiming Zhang, Xiaodong An, Wei Gao, Qianli Li
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Lycopene colorant having fresh-keeping function, preparation method therefor and application thereof
Patent number: 11540537Abstract: Disclosed is a lycopene food colorant having a fresh-keeping function. The food colorant is prepared from the following raw materials in parts by weight: 1-3 parts of a lycopene crystal, 5-20 parts of an emulsifier, 0.5-5 parts of an antioxidant, 60-70 parts of glycerol, and 10-20 parts of water. The food colorant is prepared by mixing the raw materials and then emulsifying and grinding same. The granularity of the obtained lycopene colorant is moderate; the tone is suitable for coloring a minced fillet product; the lycopene colorant has high tinting strength, achieves a bright color, and has the effect of triggering myoglobin, so that the minced fillet product has a bright color and appears fresher; the lycopene colorant further has a fresh-keeping function and can kill some food microorganisms, so as to keep food fresh and prolong the shelf life.Type: GrantFiled: June 29, 2020Date of Patent: January 3, 2023Assignee: Chenguang Biotech Group Co., Ltd.Inventors: Jianzhong Xu, Xinchao Jia, Hong Tian, Wei Gao, Hongxia Wang, Lijuan Jiao -
Patent number: 11499052Abstract: The present invention relates to a method for preparing lycopene crystals with high purity and low harm. The method comprises the following steps: (1) mixing lycopene oleoresin with a mixed solvent consisting of an alkane and a lower alcohol, and heating and stirring the resultant for dissolution to form a homogenous solution; (2) cooling the homogenous solution for crystallization, filtering the resultant to obtain a filter cake; and (3) washing the filter cake successively using a lower alcohol and an alkane, and drying the resultant to obtain lycopene crystals. According to the method provided by the present invention, lycopene crystals can be obtained using a mixed solvent by means of one step crystallization, and the crystal content is further improved and harmful substances in the crystals are reduced by means of a two-step crystal washing process to obtain lycopene crystals with high purity and low harm.Type: GrantFiled: October 25, 2017Date of Patent: November 15, 2022Assignee: CHENGUANG BIOTECH GROUP CO., LTD.Inventors: Qingguo Lu, Yunhe Lian, Zhiming Zhang, Xiaodong An, Qianli Li, Wei Gao
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Patent number: 11278856Abstract: A lutein microcapsule formulation and preparation method thereof, the formulation comprising the following ingredients: lutein crystals, a water-soluble emulsifier, an oil-soluble antioxidant, a wall material, a filler, a water-soluble antioxidant, and purified water. The preparation method comprises: dissolving the lutein crystals and the oil-soluble antioxidant in the water-soluble emulsifier to obtain an oil phase; adding the wall material, the water-soluble antioxidant, and the filler to the purified water to obtain a water phase; adding the oil phase to the water phase, grinding to obtain a particle size of the liquid emulsion of less than 100 nm, and granulating.Type: GrantFiled: January 28, 2015Date of Patent: March 22, 2022Assignee: CHENGUANG BIOTECH GROUP CO., LTDInventors: Qingguo Lu, Jianzhong Xu, Yunhe Lian
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Publication number: 20210230200Abstract: Disclosed is an industrial method for simultaneously preparing Stevia rebaudiana chlorogenic acid and stevioside. The industrial method includes carrying out alcohol extraction on Stevia rebaudiana which is used as a raw material, and then adjusting the feed liquid state to allow chlorogenic acid to be in a free molecular state; carrying out extraction separation by a water-insoluble moderate-polarity organic solvent; enriching the Stevia rebaudiana chlorogenic acid in an organic layer; and enriching the stevioside in a water layer.Type: ApplicationFiled: March 29, 2021Publication date: July 29, 2021Applicant: Chenguang Biotech Group Co., Ltd.Inventors: Yunhe LIAN, Meili XU, Wei GAO, Zhiping NIU, Yanfang WANG
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Publication number: 20210230204Abstract: An industrialization method for comprehensive utilization of Stevia rebaudiana. The major improvement is in that the Stevia rebaudiana is extracted by using a high-concentration alcohol solution, then the extracted solution is purified by using an organic solvent, and the pH of the extracted solution is adjusted to be alkaline according to the acidic characteristic of chlorogenic acid to enable the chlorogenic acid to be formed into a salt and have an increased polarity so as to achieve effective separation of the chlorogenic acid and a glucoside component in an adsorption process. The method allows the high-quality stevioside and chlorogenic acid to be obtained, significantly improves the comprehensive utilization rate of Stevia rebaudiana, reduces the waste of natural Stevia rebaudiana resources, reduces the resource consumption in a production process, reduces waste discharge, and is a high-benefit green production process.Type: ApplicationFiled: March 30, 2021Publication date: July 29, 2021Applicant: Chenguang Biotech Group Co., Ltd.Inventors: Meili XU, Yunhe LIAN, Hong TIAN, Wei GAO, Yachao XU
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LYCOPENE COLORANT HAVING FRESH-KEEPING FUNCTION, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
Publication number: 20200329747Abstract: Disclosed is a lycopene food colorant having a fresh-keeping function. The food colorant is prepared from the following raw materials in parts by weight: 1-3 parts of a lycopene crystal, 5-20 parts of an emulsifier, 0.5-5 parts of an antioxidant, 60-70 parts of glycerol, and 10-20 parts of water. The food colorant is prepared by mixing the raw materials and then emulsifying and grinding same. The granularity of the obtained lycopene colorant is moderate; the tone is suitable for coloring a minced fillet product; the lycopene colorant has high tinting strength, achieves a bright color, and has the effect of triggering myoglobin, so that the minced fillet product has a bright color and appears fresher; the lycopene colorant further has a fresh-keeping function and can kill some food microorganisms, so as to keep food fresh and prolong the shelf life.Type: ApplicationFiled: June 29, 2020Publication date: October 22, 2020Applicant: Chenguang Biotech Group Co., Ltd.Inventors: Jianzhong XU, Xinchao JIA, Hong TIAN, Wei GAO, Hongxia WANG, Lijuan JIAO -
Patent number: 10802006Abstract: A method for identifying the adulteration of a pine bark extract or a peanut skin extract in a grape seed extract using HPLC fingerprint spectrums. The method includes 1) establishing HPLC fingerprint spectrums of the three extracts; 2) determining characteristic peaks of pine bark extract and peanut skin extract; 3) testing a grape seed extract sample using liquid chromatography detection to identify the adulteration of pine bark extract or peanut skin extract in the sample according to whether the chromatogram contains the characteristic peaks of pine bark extract and/or peanut skin extract, wherein the addition of more than 3% of adulterants can be accurately identified. The method has good stability and reproducibility, high efficiency, obvious identification characteristics, provides a theoretical basis for the identification of the plant sources of grape seed extracts, and is conducive to promoting the healthy development of the plant extract industry.Type: GrantFiled: September 9, 2016Date of Patent: October 13, 2020Assignee: Chenguang Biotech Group, Co. Ltd.Inventors: Wei Gao, Li Zhou, Qingshan Yang, Lei Wang, Yunhe Lian
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Publication number: 20200297655Abstract: The present invention discloses a method for preparing a lycopene micro-capsule powder, wherein lycopene is fully mixed with an aqueous phase to obtain a lycopene emulsion, and the emulsion is then ground to a particle size less than 1 ?m, and spray dried. The aqueous phase comprises: a gelatin enzymatic hydrolysate with a molecular weight of 5,000-10,000 Da, disaccharide, polysaccharide, and an antioxidant. The disaccharide is one or more of sucrose, maltose and lactose; and the polysaccharide is one or more of pullulan and chitosan.Type: ApplicationFiled: June 8, 2020Publication date: September 24, 2020Applicant: Chenguang Biotech Group Co.,Ltd.Inventors: Wei GAO, Jianzhong XU, Xiangyu YANG, Hong TIAN, Yamei LI, Xinchao JIA
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Publication number: 20200255765Abstract: A continuous distillation process comprises the following steps: putting a material into a multilayer distillation tower to enable the material to sequentially undergo preheating, extrusion pricking, steam distillation, meal roasting, drying and cooling treatment, condensing essential oil-containing steam, and carrying out water separation, so as to obtain an essential oil.Type: ApplicationFiled: September 27, 2018Publication date: August 13, 2020Applicant: CHENGUANG BIOTECH GROUP CO., LTD.Inventors: Lijun Qi, Shaowei Han, Shaodong Ji, Fengfei Li, Wenjiang Yang, Haijun Bao
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Publication number: 20190025265Abstract: Disclosed is a method for identifying grape seed extract authenticity using the HPLC fingerprint spectrum, and in particular, a method for identifying the adulteration of a pine bark extract or a peanut skin extract in a grape seed extract. The method comprises the following steps: 1) establishing the HPLC fingerprint spectrums of the grape seed extract, the pine bark extract and the peanut skin extract, respectively; 2) determining a characteristic peak of pine bark extract and a characteristic peak of peanut skin extract; 3) subjecting the grape seed extract sample to be tested to liquid chromatography detection, identifying the adulteration of the pine bark extract or the peanut skin extract in the sample to be tested according to whether the chromatogram contains the characteristic peaks of the pine bark extract and/or the peanut skin extract, wherein the addition of more than 3% of adulterants can be accurately identified.Type: ApplicationFiled: September 9, 2016Publication date: January 24, 2019Applicant: Chenguang Biotech Group Co., Ltd.Inventors: Wei Gao, Li Zhou, Qingshan Yang, Lei Wang, Yunhe Lian
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Publication number: 20180338513Abstract: Disclosed is a method for removing benzo[?]pyrene from a liposoluble natural extract. The method of the present invention comprises adding a suitable solvent to a crude natural extract product so as to obtain a mixed material; heating the mixed material, stirring until uniform, cooling and layering, and then separating the upper layer from the lower layer so as to obtain a precipitate and a filtrate; washing the precipitate with a small amount of a solvent so as to obtain a washed product and a washing solution; removing the solvent from the washed product at a low temperature so as to obtain a finished product; and directly recycling the filtrate and the washing solution as solvents. The present method achieves the purification of the crude natural extract product and the removal of benzo[?]pyrene in one step, and is a novel method which is simple, highly efficient, feasible and easy for industrial applications.Type: ApplicationFiled: November 1, 2016Publication date: November 29, 2018Applicant: Chenguang Biotech Group Co., Ltd.Inventors: Yunhe LIAN, Wei GAO, Yuanxin CHENG, Xiangyu YANG, Xiaodong AN, Zhipeng DUAN, Zhiming ZHANG
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Patent number: 9765062Abstract: The present invention relates to a method for producing silymarin. The method comprises: pressing silybum marianum seeds to obtain silymarin powder, and soaking the silymarin powder by using alkaline water; extracting, by using acetone, the silymarin powder soaked by using alkaline water, and performing filtering and concentration on the extracted liquid to obtain a concentrated solution; and performing extraction on the concentrated solution by using a non-polar solvent, performing separation to obtain a non-polar solvent layer and an acetone layer, and concentrating and drying the acetone layer to obtain silymarin. The method can greatly improve the extraction efficiency and the yield, shorten the extraction time, needs simple processes and low cost and thoroughly remove residual oil, so that the product has a low impurity, high product quality and a high purity; and the method is applicable to industrial production and has a great application prospect and economic value.Type: GrantFiled: December 30, 2013Date of Patent: September 19, 2017Assignee: Chenguang Biotech Group Co., Ltd.Inventors: Qingguo Lu, Yunhe Lian, Hong Tian, Xinying Cheng, Zhipeng Duan
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Patent number: 9434886Abstract: A process for extracting lycopene, comprising the following steps: pressing and dehydrating tomato pomace which is the by-products of tomato processing production, then drying it to control the water content in the range from 10% to 20%; crushing the dried tomato pomace, and separating tomato skins and tomato seeds by air blast process, granulating the separated tomato skins and extracting them, then purifying by removing impurity from the extracted lycopene with active carbon.Type: GrantFiled: December 31, 2011Date of Patent: September 6, 2016Assignee: Chenguang Biotech Group Co. Ltd.Inventors: Qingguo Lu, Yunhe Lian, Wenjie Han, Yuhai Tong, Xuehui Su, Xiaodong An, Junqiang Zhang
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Patent number: 8921615Abstract: Disclosed a process for preparing a xanthophyll crystal, comprising: dissolving the plant extract containing a xanthophyll ester in n-hexane, then filtering the mixture; adding acetone to the filtrate, filtering and collecting a filter cake; mixing the filter cake with soybean oil and ethanol uniformly; saponifying the mixed solution with alkaline aqueous solution; then adding an acidic solution thereto until the mixed solution becomes acidic, concentrating under reduced pressure to obtain a pasty substance; adding n-hexane to the pasty saponified product, standing still and then conducting a solid-liquid separation; washing the resulting solid substance with deionized water; adding a mixed solvent to the washed solid substance, dissolving it with stirring; and then adding n-hexane thereto and standing still to recrystallize.Type: GrantFiled: December 31, 2011Date of Patent: December 30, 2014Assignee: Chenguang Biotech Group Co. Ltd.Inventors: Qingguo Lu, Yunhe Lian, Xuehui Su, Xiaodong An, Yuanxin Cheng, Lijun Qi
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Publication number: 20140316175Abstract: A process for extracting lycopene, comprising the following steps: pressing and dehydrating tomato pomace which is the by-products of tomato processing production, then drying it to control the water content in the range from 10% to 20%; crushing the dried tomato pomace, and separating tomato skins and tomato seeds by air blast process, granulating the separated tomato skins and extracting them, then purifying by removing impurity from the extracted lycopene with active carbon.Type: ApplicationFiled: December 31, 2011Publication date: October 23, 2014Applicant: CHENGUANG BIOTECH GROUP CO. LTD.Inventors: Qingguo Lu, Yunhe Lian, Wenjie Han, Yuhai Tong, Xuehui Su, Xiaodong An, Junqiang Zhang
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Publication number: 20140303406Abstract: Disclosed a process for preparing a xanthophyll crystal, comprising: dissolving the plant extract containing a xanthophyll ester in n-hexane, then filtering the mixture; adding acetone to the filtrate, filtering and collecting a filter cake; mixing the filter cake with soybean oil and ethanol uniformly; saponifying the mixed solution with alkaline aqueous solution; then adding an acidic solution thereto until the mixed solution becomes acidic, concentrating under reduced pressure to obtain a pasty substance; adding n-hexane to the pasty saponified product, standing still and then conducting a solid-liquid separation; washing the resulting solid substance with deionized water; adding a mixed solvent to the washed solid substance, dissolving it with stirring; and then adding n-hexane thereto and standing still to recrystallize.Type: ApplicationFiled: December 31, 2011Publication date: October 9, 2014Applicant: CHENGUANG BIOTECH GROUP CO., LTD.Inventors: Qingguo Lu, Yunhe Lian, Xuehui Su, Xiaodong An, Yuanxin Cheng, Lijun Qi