Abstract: A method for mass rearing of insects. A web including a plurality of wells is provided. Insect eggs or larvae and growth medium are loaded in the wells. The wells are covered. The web is rolled up. The eggs or larvae are incubated during eggs hatch and larval growth. The web is unrolled and the larvae harvested.
Type:
Application
Filed:
February 10, 2006
Publication date:
December 4, 2008
Applicant:
Chesapeake Perl, Inc.
Inventors:
Nikolai A. Van Beek, David C. Davis, Thomas A. Curran, Wayne C. Taylor
Abstract: This invention relates, e.g., to transgenic insects, or progeny thereof, whose cells contain at least one genomically integrated, expressible, nucleic acid encoding two or more of a set of Nglycosylation enzymes that can glycosylate a heterologous protein with a mammalianized (e.g., humanized) glycosylation pattern. The glycosylation genes are preferably expressed in the insect cells in catalytic amounts. Also described are methods to use such a transgenic insect to produce heterologous, mammalianized polypeptides of interest.
Type:
Application
Filed:
October 28, 2004
Publication date:
March 22, 2007
Applicant:
Chesapeake Perl, Inc.
Inventors:
Donald Jarvis, Nikolai Beek, Malcolm Fraser