Patents Assigned to Children's Medical Research Instiute
  • Methods and Agents for Inhibiting Dynamin-Dependent Endocytosis
    Publication number: 20070225363
    Abstract: There are disclosed methods for inhibiting dynamin-dependent endocytosis in cells comprising treating the cells with an effective amount of a compound of formula (I), or a dimeric tyrphostin, physiologically acceptable salt, or prodrug thereof. Compounds useful in the methods described are also provided. The inhibition of dynamin-dependent endocytosis of cells is applicable to the treatment of epilepsy and neurological disorders and conditions.
    Type: Application
    Filed: November 22, 2004
    Publication date: September 27, 2007
    Applicants: the University of Newcastle Research Associates Ltd., Children's Medical Research Instiute
    Inventors: Adam McCluskey, Phillip Robinson, Timothy Hill