Patents Assigned to Ciba-Geigy Corporation a Corp. of New York
  • Production of thrombin inhibitors
    Patent number: 6410272
    Abstract: A method for the production and secretion of proteins with hirudin activity in an eukaryotic host organism is provided. There are also provided hybrid vectors comprising a DNA sequence encoding a signal peptide upstream of and in reading frame with the structural gene for desulphatohirudin, and eukaryotic host organisms transformed with said hybrid vectors.
    Type: Grant
    Filed: February 27, 1990
    Date of Patent: June 25, 2002
    Assignee: Ciba-Geigy Corporation a Corp. of New York
    Inventors: Bernd Meyhack, Walter Märki, Jutta Heim