Patents Assigned to Cidara Therapeutics, Inc.
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Patent number: 11833213Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).Type: GrantFiled: April 21, 2021Date of Patent: December 5, 2023Assignee: Cidara Therapeutics, Inc.Inventors: James M. Balkovec, Daniel C. Bensen, Allen Borchardt, Thomas P. Brady, Zhi-Yong Chen, Jason Cole, Quyen-Quyen Thuy Do, Simon Doehrmann, Wanlong Jiang, Thanh Lam, Alain Noncovich, Leslie W. Tari
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Patent number: 11819533Abstract: The disclosure features non-irritating pharmaceutical compositions containing CD101 in pharmaceutical acceptable salt (e.g., CD101 acetate) or neutral form. The pharmaceutical compositions can be intravenously administered to a subject to treat fungal infections (e.g., candidiasis) in the subject.Type: GrantFiled: December 1, 2021Date of Patent: November 21, 2023Assignee: Cidara Therapeutics, Inc.Inventors: Kenneth Bartizal, Paul Daruwala, David Hughes, Martin Patrick Hughes, Navdeep B. Malkar, Balasingam Radhakrishnan, Anuradha Vaidya
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Patent number: 11712459Abstract: The disclosure features pharmaceutical compositions, methods, and kits featuring dosing regimens and CD101, or a pharmaceutical acceptable salt or neutral form thereof (e.g., CD101 acetate).Type: GrantFiled: March 15, 2017Date of Patent: August 1, 2023Assignee: Cidara Therapeutics, Inc.Inventors: Kenneth Bartizal, Paul Daruwala, Jeffrey Brian Locke, Voon Ong, Taylor Sandison, Dirk Thye
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Patent number: 11654196Abstract: The invention features pharmaceutical compositions, methods, and kits featuring dosing gimens and oral dosage formulations for administration of echinocandin class compounds.Type: GrantFiled: July 2, 2020Date of Patent: May 23, 2023Assignee: Cidara Therapeutics, Inc.Inventors: Balasingam Radhakrishnan, Kenneth Duke James, Jr., Anuradha Vaidya, Karen Polowy
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Patent number: 11524980Abstract: The present invention relates to echinocandin cyclopeptides and to methods for preparing echinocandin cyclopeptides.Type: GrantFiled: June 14, 2019Date of Patent: December 13, 2022Assignee: Cidara Therapeutics, Inc.Inventors: David Hughes, Martin Patrick Hughes, Robert Michael Hughes, Balasingam Radhakrishnan, Yannick Borguet, Steven McIntyre
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Patent number: 11510992Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).Type: GrantFiled: April 21, 2021Date of Patent: November 29, 2022Assignee: Cidara Therapeutics, Inc.Inventors: Allen Borchardt, Thomas P. Brady, Zhi-Yong Chen, Thanh Lam, Leslie W. Tari
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Patent number: 11197909Abstract: The disclosure features non-irritating pharmaceutical compositions containing CD101 in pharmaceutical acceptable salt (e.g., CD101 acetate) or neutral form. The pharmaceutical compositions can be intravenously administered to a subject to treat fungal infections (e.g., candidiasis) in the subject.Type: GrantFiled: July 11, 2018Date of Patent: December 14, 2021Assignee: Cidara Therapeutics, Inc.Inventors: Kenneth Bartizal, Paul Daruwala, David Hughes, Martin Patrick Hughes, Navdeep B. Malkar, Balasingam Radhakrishnan, Anuradha Vaidya
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Publication number: 20210228727Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).Type: ApplicationFiled: March 5, 2021Publication date: July 29, 2021Applicants: Cidara Therapeutics, Inc., Cidara Therapeutics, Inc.Inventors: James M. BALKOVEC, Daniel C. BENSEN, Allen BORCHARDT, Thomas P. BRADY, Zhi-Yong CHEN, Jason COLE, Quyen-Quyen Thuy DO, Simon DOEHRMANN, Wanlong JIANG, Thanh LAM, Alain NONCOVICH, Leslie W. TARI
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Publication number: 20210220478Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).Type: ApplicationFiled: March 5, 2021Publication date: July 22, 2021Applicant: Cidara Therapeutics, Inc.Inventors: James M. BALKOVEC, Daniel C. BENSEN, Allen BORCHARDT, Thomas P. BRADY, Zhi-Yong CHEN, Jason COLE, Quyen-Quyen Thuy DO, Simon DOEHRMANN, Wanlong JIANG, Thanh LAM, Alain NONCOVICH, Leslie W. TARI
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Patent number: 10780144Abstract: The disclosure relates to methods of prophylactic and therapeutic treatments of a Pneumocystis infection (i.e., an infection caused by Pneumocystis jirovecii) in a subject by administering to the subject a compound of any of formulas (I)-(III) (e.g., a salt of Compound 1, or a neutral form thereof). The disclosure also relates to methods of inhibiting the replication of a Pneumocystis spp. The methods of the disclosure can be useful in immunocompromised subjects.Type: GrantFiled: August 1, 2019Date of Patent: September 22, 2020Assignee: Cidara Therapeutics, Inc.Inventors: Kenneth Bartizal, Paul Daruwala, Voon Ong, Maureen Roden, Taylor Sandison, Dirk Thye
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Patent number: 10702573Abstract: The invention features pharmaceutical compositions, methods, and kits featuring dosing gimens and oral dosage formulations for administration of echinocandin class compounds.Type: GrantFiled: June 25, 2018Date of Patent: July 7, 2020Assignee: Cidara Therapeutics, Inc.Inventors: Balasingam Radhakrishnan, Kenneth Duke James, Jr., Anuradha Vaidya, Karen Polowy
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Patent number: 10369188Abstract: The disclosure relates to methods of prophylactic and therapeutic treatments of a Pneumocystis infection (i.e., an infection caused by Pneumocystis jirovecii) in a subject by administering to the subject a compound of any of formulas (1)-(111) (e.g., a salt of Compound 1, or a neutral form thereof). The disclosure also relates to methods of inhibiting the replication of a Pneumocystis spp. The methods of the disclosure can be useful in immunocompromized subjects.Type: GrantFiled: January 6, 2017Date of Patent: August 6, 2019Assignee: Cidara Therapeutics, Inc.Inventors: Kenneth Bartizal, Paul Daruwala, Voon Ong, Maureen Roden, Taylor Sandison, Dirk Thye
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Patent number: 10016479Abstract: The invention features pharmaceutical compositions, methods, and kits featuring dosing gimens and oral dosage formulations for administration of echinocandin class compounds.Type: GrantFiled: December 7, 2016Date of Patent: July 10, 2018Assignee: Cidara Therapeutics, Inc.Inventors: Balasingam Radhakrishnan, Kenneth Duke James, Jr., Anuradha Vaidya, Karen Polowy
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Patent number: 9676821Abstract: The invention features echinocandin class compounds. The compounds can be useful for the treatment of fungal infections.Type: GrantFiled: November 24, 2015Date of Patent: June 13, 2017Assignee: Cidara Therapeutics, Inc.Inventors: Kenneth Duke James, Jr., Christopher Patrick Laudeman, Navdeep Balkrishna Malkar, Balasingam Radhakrishnan
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Patent number: 9526835Abstract: The invention features pharmaceutical compositions, methods, and kits featuring dosing gimens and oral dosage formulations for administration of echinocandin class compounds.Type: GrantFiled: March 14, 2013Date of Patent: December 27, 2016Assignee: Cidara Therapeutics, Inc.Inventors: Balasingam Radhakrishnan, Kenneth Duke James, Jr., Anuradha Vaidya, Karen Polowy
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Publication number: 20160213742Abstract: Compositions and methods for the treatment of fungal infections including compounds containing a pathogen pattern recognition receptor ligand and a ? 1,3-glucan synthase inhibitor are disclosed. In particular, compounds containing a lipopeptide moiety and a formyl peptide receptor ligand can be used in the treatment of fungal infections caused by a fungus of the genus Aspergillus or Candida.Type: ApplicationFiled: September 4, 2014Publication date: July 28, 2016Applicants: Cidara Therapeutics, Inc., Cidara Therapeutics, Inc.Inventors: Kevin Michael FORREST, James Kevin JUDICE, H. Shaw WARREN, James Michael BALKOVEC, Thomas Patrick BRADY
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Patent number: 9217014Abstract: The invention features echinocandin class compounds. The compounds can be useful for the treatment of fungal infections.Type: GrantFiled: April 1, 2014Date of Patent: December 22, 2015Assignee: Cidara Therapeutics, Inc.Inventors: Kenneth Duke James, Jr., Christopher Patrick Laudeman, Navdeep Balkrishna Malkar, Balasingam Radhakrishnan
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Publication number: 20150087583Abstract: The invention features pharmaceutical compositions, methods, and kits featuring dosing gimens and oral dosage formulations for administration of echinocandin class compounds.Type: ApplicationFiled: March 14, 2013Publication date: March 26, 2015Applicant: Cidara Therapeutics, Inc.Inventors: Balasingam Radhakrishnan, Kenneth Duke James, JR., Anuradha Vaidya, Karen Polowy