Patents Assigned to City University
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Patent number: 11991862Abstract: The present invention provides a microchannel heat sink with plural microchannels, each having a respective inlet and outlet to permit flow, in particular two-phase flow, of a working fluid. The plural microchannels are arranged such that adjacent microchannels accommodate flow of working fluid in opposite directions and are thermally coupled to each other to enable heat exchange between the corresponding adjacent microchannels. In one aspect, a microchannel inlet is positioned at an angle (e.g., 90 degrees) with respect to its outlet. The plural microchannels define parallel longitudinal axes that are optionally arranged on the same plane and/or side-by-side in a single layer. Further, in one aspect, each microchannel cross-sectional area increases as the channel length progresses from an upstream end (e.g., adjacent to the inlet) to a downstream end (e.g., adjacent to the outlet) of the corresponding microchannel.Type: GrantFiled: September 14, 2021Date of Patent: May 21, 2024Assignee: City University of Hong KongInventors: Chin Pan, Xingchi Jiang, Shiwei Zhang
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Patent number: 11988454Abstract: A thermochemical energy storage system. The system includes a membrane-based thermochemical reactor having a solution channel having an absorbent-containing solution flowing therethrough and a refrigerant channel having a refrigerant flowing therethrough along with first and second fluid channels. A porous membrane is positioned between the refrigerant channel and the solution channel; the porous membrane permits flow of vapor molecules therethrough while restricting flow of absorbent molecules. The system further includes a solution storage repository in fluid communication with the solution channel and a refrigerant repository in fluid communication with the refrigerant channel. The system can be used in high-density, high-efficiency, and low-temperature energy storage systems. The membrane-based reactor offers a large specific surface area and integrates solution/refrigerant flows, which enables formation of a highly compact reactor exhibiting strong heat/mass transfer.Type: GrantFiled: August 27, 2021Date of Patent: May 21, 2024Assignee: City University of Hong KongInventors: Wei Wu, Zhixiong Ding, Yunren Sui, Chong Zhai, Zengguang Sui
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Patent number: 11986830Abstract: A device for storage and transport of biological samples. Multiple trays are assembled into a stack with sample tubes constrained between adjacent trays. The surface of each tray has radial grooves sized to hold the sample tubes. Each tray is secured to an adjacent tray with a bolt or snap-fit connector.Type: GrantFiled: January 27, 2021Date of Patent: May 21, 2024Assignee: Research Foundation of the City University of New YorkInventor: Michael Zions
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Patent number: 11988093Abstract: An inflatable folding tunnel reinforcement structure and a construction method thereof are provided. The inflatable folding tunnel reinforcement structure includes an inflation port, an airbag, a water blocking net, a steel plate, a scissor folding mechanism, a vertical support plate, an arc-shaped support plate, drainage channels, an upper support rod, a lower support rod, a locking pin, a threaded steel rod, a rolling connection pin, and an induction motor, where the upper support rod and the lower support rod are unfolded in opposite directions to a preset position through the steel rod; and the drainage channels are configured to perform water guidance and resistance for a leakage-proofing purpose. The construction method includes: preparation before construction, device fixation, on-site construction, structural inspection, and site cleaning.Type: GrantFiled: January 4, 2023Date of Patent: May 21, 2024Assignee: Hangzhou City UniversityInventors: Gang Wei, Tianbao Xu, Xin Li, Tianyu Zhu, Shuangyan Lin, Luju Liang, Chengbao Hu, Xiao Wang
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Patent number: 11987866Abstract: An alloy consisting of titanium, zirconium, cobalt, and nickel, and its fabrication.Type: GrantFiled: July 22, 2022Date of Patent: May 21, 2024Assignee: City University of Hong KongInventors: Yong Yang, Hang Wang
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Patent number: 11986659Abstract: Methods, devices, and systems for treating spasticity, hypertonia or dystonia are disclosed. Treatment involves applying a source of direct current to one or more locations in a subject (animal, human, or other sentient being). Locations for application of direct current include the spinal column, peripheral nerves, and the cranium. The delivery of direct current is adjusted to change biological activity of or level of gene expression and/or protein expression of target molecule NKCC1.Type: GrantFiled: March 22, 2019Date of Patent: May 21, 2024Assignee: Research Foundation of the City University of New YorkInventor: Zaghloul Ahmed
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Patent number: 11986482Abstract: Methods of inhibiting endosomal trafficking of PD-L1, inducing PD-L1 secretion via exosomes, decreasing PD-L1 level at a surface of a cancer or tumor cell, and treating a cancer or tumor through promoting T cell immune response in a subject suffering from a cancer or tumor, includes the step of administering a compound of Formula I to various cells. Also, a composition to treat a cancer or a tumor, includes a compound of Formula I and an anti-PD-1 antibody.Type: GrantFiled: March 21, 2022Date of Patent: May 21, 2024Assignees: City University of Hong Kong, 6J Biotechnology (Hong Kong) LimitedInventors: Jianbo Yue, Qingru Zhang, Zuodong Ye, Wang Peng
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Patent number: 11986525Abstract: Provided herein is a method of treating a traumatic brain injury in a subject in need thereof, the method including administering to the subject a therapeutically effective amount of radiation. The methods can improve motor function recovery and reverse motor function deficits after traumatic brain injury and/or ischemic stroke in a subject.Type: GrantFiled: October 5, 2021Date of Patent: May 21, 2024Assignee: City University of Hong KongInventors: Chi Him Eddie Ma, Ngan Pan Bennett Au
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Patent number: 11971951Abstract: Systems and methods which provide a motion sensor data-driven framework for sports action recognition and/or assessment using a wearable sensor are described. A motion sensor data-driven system may provide real-time kinematical analysis to athletes engaged in active competition or training sessions under typical competition or training conditions. Analysis of motion sensor data provided according to embodiments may operate to recognize instances of one or more particular sports actions performed by an athlete and/or assess the skill of the athlete from analysis of one or more sports actions. A motion sensor data processing platform of embodiments of a motion sensor data-driven system may comprise a processor-based system configured to receive and analyze data regarding the movement of an athlete's limb reported by a wearable sensor device comprising a micro inertial measurement unit configuration for capturing and reporting data regarding the movement of an athlete's limb.Type: GrantFiled: June 21, 2018Date of Patent: April 30, 2024Assignee: City University of Hong KongInventors: Yufan Wang, Wen Jung Li, Ho Man Chan, Guanglie Zhang
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Publication number: 20240132887Abstract: Disclosed herein are, inter alia, inhibitors of protein arginine methyltransferase 9 and pharmaceutical compositions thereof, and methods comprising the use of protein arginine methyltransferase 9 inhibitors for the treatment of a protein arginine methyltransferase 9-modulated disease or disorder, such as a hematological cancer.Type: ApplicationFiled: October 6, 2023Publication date: April 25, 2024Applicants: City of Hope, Western University of Health SciencesInventors: Ling Li, Haojie Dong, Lei Zhang, Xin He, Yun Lyna Luo, Yi-Chun Lin
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Patent number: 11963788Abstract: The present invention provides a graph-based prostate diagnosis network (GPD-Net) and a method for using the same to predict a prostate health status of a patient from a 3D magnetic resonance imaging (MRI) scan containing a plurality of 2D MRI slices. The GPD-Net only demands patient-level annotations of MRI scan for training by formulating the diagnosis task of 3D prostate MRI scan in a multi-instance learning (MIL) strategy, and regarding each 2D MRI slice in the 3D prostate MRI scan as an instance. The GPD-Net includes a plurality of importance-guided graph convolutional layers to explore the diagnostic information with the importance-based topology. The present invention provides accurate prediction of prostate diseases and achieve more reliable diagnosis from MRI scans, therefore can effectively alleviate the workload of clinician in viewing the slices of MRI scan.Type: GrantFiled: December 17, 2021Date of Patent: April 23, 2024Assignee: City University of Hong KongInventors: Yixuan Yuan, Zhen Chen
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Patent number: 11968769Abstract: A dielectric barrier discharging tube, which has a synergistic column of needle electrodes to utilize a plurality of channels to adsorb catalysts, is provided. The dielectric barrier discharging tube includes: a quartz tube, a high-voltage pole, an inner electrode, and a plurality discharging needle sets. Two catalytic blocks are arranged respectively on two sides of each set discharging needles. Each catalytic block defines at least one inclined inner channel and at least one inclined outer channel. A higher end of each channel faces towards the discharging needle, and a lower end of each channel faces towards the discharging needle.Type: GrantFiled: December 21, 2023Date of Patent: April 23, 2024Assignee: HANGZHOU CITY UNIVERSITYInventors: Qi Qiu, Pengfei Wang, Qinmin Yang, Hao Chen
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Patent number: 11968904Abstract: The present invention provides a flexible piezoelectric composite including a three-dimensional interconnected piezoelectric ceramic framework based on a porous organic template with sufficient stiffness and infiltrated with a flexible polymer matrix. A method for fabricating the flexible piezoelectric composition is also described herein.Type: GrantFiled: July 5, 2021Date of Patent: April 23, 2024Assignee: City University of Hong KongInventors: Zhengbao Yang, Ying Hong
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Publication number: 20240125767Abstract: The present invention provides drug toxicity evaluation platforms (such as an evaluation method and a kit therefor) that enable detailed analysis of the possibility and the like of developing drug-induced damage (such as DILI) to the liver and other organs. The method for evaluating drug toxicity of the present invention includes: a step of adding a drug to a co-culture system of an organoid and blood cells; and a step of evaluating the toxicity of the drug to the organoid.Type: ApplicationFiled: October 16, 2020Publication date: April 18, 2024Applicants: Public University Corporation Yokohama City University, Takeda Pharmaceutical Company LimitedInventors: Takanori TAKEBE, Norikazu SAIKI
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Patent number: 11962259Abstract: A drive system is disclosed which applies to a six-phase integrated permanent magnet synchronous motor. The motor includes a set of six-phase half-bridge drive system and a thermistor monitoring system for monitoring the temperature of the six-phase half-bridge drive system. Aiming at the problem that the six-phase drive system is complicated and has many components, the invention adopts a grouping method to divide the six-phase drive system into two sets of three-phase drive half-bridges. To provide stability for long term operation, a thermistor is used to accurately measure the temperature changes.Type: GrantFiled: December 27, 2021Date of Patent: April 16, 2024Assignee: CITY UNIVERSITY OF HONG KONGInventors: Chunhua Liu, Senyi Liu
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Patent number: 11961618Abstract: The present invention provides a task interaction network which can jointly perform, based on multi parametric-magnetic resonance imaging scan images, a segmentation task to locate prostate cancer areas and a classification task to access aggressiveness of lesions. The task interaction network comprises a backbone network, an auxiliary segmentation branch, a classification branch having a lesion awareness module, and a main segmentation branch having a category allocation module. The auxiliary segmentation branch is utilized to predict an initial lesion mask as location guidance information for the classification branch to perform the classification task. The lesion awareness module is configured to refine the initial lesion mask to make it more accurate. Moreover, weights used in classification branch can serve as the category prototypes for generating category guidance features via the category allocation module to assist the main segmentation branch to perform the segmentation task.Type: GrantFiled: November 17, 2021Date of Patent: April 16, 2024Assignee: City University of Hong KongInventors: Yixuan Yuan, Meilu Zhu
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Patent number: 11958620Abstract: The present disclosure relates to a hydrogen electric hybrid power plant for a hovercar. The hydrogen electric hybrid power plant comprises a first-stage duct, a transition duct and a second-stage duct. An air outlet end of the first-stage duct is connected to the second-stage duct through the transition duct. A hydrogen reactor is arranged in the first-stage duct, and the hydrogen reactor is fixed with the first-stage duct through a plurality of supporting pieces A. A primary filter screen is arranged at a front end of the first-stage duct and fixed on the first-stage duct through a hoop, so that low-altitude sundries and dust are prevented from entering the reactor. A return pipe is arranged, and the problems of oxygen supply, heat dissipation and cooling and the like of the hydrogen reactor are solved through ducted airflow. A motor power supply requirement of a ducted fan is met.Type: GrantFiled: May 16, 2023Date of Patent: April 16, 2024Assignee: HANGZHOU CITY UNIVERSITYInventor: Xinfeng Zhang
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Patent number: 11958869Abstract: Disclosed herein are ruthenium arene Schiff-base complex and uses thereof. The ruthenium arene Schiff-base complex disclosed herein has the structure of formula (I), wherein, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, and R12 are independently H, alkyl, alkoxyl, or halo; R13, R14, R15, R16, and R17 are independently H, alkyl, alkoxyl, hydroxy, halo, —C(?NH)NH2, —SO3H, —SO2NH2, —NR?R?, or —CONH2; or R13 and R14 are taken together to form a benzene ring, while R15, R16, and R17 are independently H, alkyl, alkoxyl, hydroxy, halo, —C(?NH)NH2, —SO3H, —SO2NH2, —NR?R?, or —CONH2; or R14 and R15 are taken together to form a benzene ring, while R13, R16, and R17 are independently H, alkyl, alkoxyl, hydroxy, halo, —C(?NH)NH2, —SO3H, —SO2NH2, —NR?R?, or —CONH2; R? and R? are independently H or alkyl; the alkyl is optionally substituted with one or more halo or hydroxy, or hydroxy; and Y is a counter anion. Also disclosed herein are methods of treating malignant neoplasm in a subject.Type: GrantFiled: April 13, 2022Date of Patent: April 16, 2024Assignee: CITY UNIVERSITY OF HONG KONGInventors: Maria Babak, Wee Han Ang, Mun Juinn Chow
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Publication number: 20240115873Abstract: The ultraviolet therapy apparatus includes a light source part having an LED light source, a controller that controls lighting of the LED light source, an input unit that inputs a set irradiation dose of a therapeutic light to be applied to a patient on the assumption that a reference light is used for the therapeutic light, a storage unit that stores at least one parameter for modifying the set irradiation dose. The controller includes a modifier that modifies the set irradiation dose on the basis of the parameter stored in the storage unit, and a lighting controller that causes the LED light source to provide the modified irradiation dose. The modified irradiation dose is derived from a degree of effect of the reference light on a human body and a degree of effect on the human body caused by the ultraviolet light output from the light source part.Type: ApplicationFiled: December 9, 2021Publication date: April 11, 2024Applicants: PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY, USHIO DENKI KABUSHIKI KAISHAInventors: Akimichi MORITA, Takashi HORIO, Tomohiko KIO, Hiroshi SHIBATA
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Patent number: 11955627Abstract: A novel anode for a zinc battery is proposed, in which zinc is provided as a coat of zinc powder onto a tin substrate, which is in turn laid over a copper substrate for a current collector. Alternatively, the coat of zinc powder is laid over titanium as the current collector. Such configurations mitigate zinc corrosion and hydrogen production.Type: GrantFiled: January 20, 2022Date of Patent: April 9, 2024Assignee: CITY UNIVERSITY OF HONG KONGInventors: Chunyi Zhi, Qing Li