Abstract: A tube dispenser for adhesive compositions and adhesive components is equipped with a sponge applicator device. The tube includes an upper neck body which is cylindrical with exterior threads so that the sponge applicator device may be attached. The sponge applicator device has a rigid cap portion with interior threads, a cylindrical top end having a longitudinal channel, an absorbent, porous applicator material covering the external opening of the longitudinal channel, and a lance centered within the threaded cap and coaxial with the longitudinal channel. The porous applicator material may be affixed to the external opening of the top end with an adhesive, or held in place by a snap ring.

Abstract: The present invention provides a novel method of sterilizing 2-Cyanoacrylate ester compositions using a combination of chemical and irradiation means, and the resulting novel compositions. The combination of monomeric 2-Cyanoacrylate and irradiation have a lethal effect on microbials, rendering sterilized compositions when the appropriate sterilization condition is achieved and when the method is applied to 2-Cyanoacrylates in sealed containers. Samples are sterilized using electron beam at doses as low as about 1 to about 5 Kgy.

Abstract: Disclosed are a sponge applicator device, and a tube dispenser for adhesive compositions and adhesive components which comprise a sponge applicator device. The tube includes an upper neck body which is cylindrical with exterior threads so that the sponge applicator cap may be attached. The sponge applicator comprises a rigid cap portion having interior threads, a cylindrical top end having a longitudinal channel, an absorbent, porous applicator material covering the external opening of said longitudinal channel, and a lance centered within the said threaded cap and coaxial with said longitudinal channel. The porous applicator material may be affixed to the end of the top end with an adhesive, or held in place by a snap ring.

Abstract: Disclosed is a method of female contraception comprising: injecting a bioabsorbable and biocompatible tissue adhesive into the fallopian tubes, and allowing the said bioabsorbable tissue adhesive to polymerize to occlude the fallopian tubes (bilaterally) to achieve contraception. When the bioabsorbable biocompatible adhesive is one which forms a simple mechanical barrier, the contraception is temporary, and would be reversed upon bioabsorbtion of the tissue adhesive. When the bioabsorbable, biocompatible adhesive is one which produces a mild inflammatory reaction resulting in the formation of a permanent scar tissue plug, the contraception would be permanent.