Patents Assigned to Clinical Technologies, Inc.
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Publication number: 20070197683Abstract: A self-etching and self-adhesive dental composition is provided, comprising a polymerizable (meth)acrylate carboxylic acid/anhydride; a copolymerizable multi-functional (meth)acrylate resin; a copolymerizable diluent monomer; and a curing system. The composition has the advantage of not requiring a separate etching and bonding step.Type: ApplicationFiled: February 22, 2007Publication date: August 23, 2007Applicant: PENTRON CLINICAL TECHNOLOGIES, INCInventors: Weitao Jia, Shuhua Jin
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Publication number: 20070169774Abstract: An aerosol medication delivery apparatus includes a fixed volume holding chamber which is constructed to allow for a uniformly mixed, concentrated bolus of medicated aerosol to be delivered with each breath. The device further includes a universal inlet, so that any standard small volume nebulizer, as well as any standard metered dose inhaler (MDI), may be utilized therewith. Also filtration can be added to address contaminated patient air and aerosol. A one-way valve is positioned in the patient mouthpiece, to help control the loss of aerosol, and thereby reduce waste.Type: ApplicationFiled: March 23, 2007Publication date: July 26, 2007Applicant: Clinical Technologies, Inc.Inventors: Robert Johnson, Robert DuBose
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Patent number: 7204245Abstract: An aerosol medication delivery apparatus includes a fixed volume holding chamber which is constructed to allow for a uniformly mixed, concentrated bolus of medicated aerosol to be delivered with each breath. The device further includes a universal inlet, so that any standard small volume nebulizer, as well as any standard metered dose inhaler (MDI), may be utilized therewith. Also filtration can be added to address contaminated patient air and aerosol. A one-way valve is positioned in the patient mouthpiece, to help control the loss of aerosol, and thereby reduce waste.Type: GrantFiled: May 15, 2001Date of Patent: April 17, 2007Assignee: Clinical Technologies, IncInventors: Robert Johnson, Robert DuBose
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Publication number: 20070049656Abstract: A curable restorative composition is disclosed, comprising a polymerizable mono(meth)acrylate resin having a vapor pressure of 1 mm Hg or less at 20° C., a plasticizer; and a curing system for the mono(meth)acrylate resin. The composition is particularly useful for making temporary restorations. Methods of used and kits comprising the composition are also disclosed.Type: ApplicationFiled: September 1, 2006Publication date: March 1, 2007Applicant: PENTRON CLINICAL TECHNOLOGIES, INCInventors: Weitao Jia, Shuhua Jin
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Publication number: 20020121275Abstract: An aerosol medication delivery apparatus includes a fixed volume holding chamber which is constructed to allow for a uniformly mixed, concentrated bolus of medicated aerosol to be delivered with each breath. The device further includes a universal inlet, so that any standard small volume nebulizer, as well as any standard metered dose inhaler (MDI), may be utilized therewith. Also filtration can be added to address contaminated patient air and aerosol. A one-way valve is positioned in the patient mouthpiece, to help control the loss of aerosol, and thereby reduce waste.Type: ApplicationFiled: May 15, 2001Publication date: September 5, 2002Applicant: CLINICAL TECHNOLOGIES, INC.Inventors: Robert Johnson, Robert DuBose
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Patent number: 6363932Abstract: An aerosol medication delivery apparatus includes a fixed volume holding chamber which is constructed to allow for a uniformly mixed, concentrated bolus of medicated aerosol to be delivered with each breath. The device further includes a universal inlet, so that any standard small volume nebulizer, as well as any standard metered dose inhaler (MDI), may be utilized therewith. Also filtration can be added to address contaminated patient air and aerosol. A one-way valve is positioned between the holding chamber and a tee piece for attaching the holding chamber to a patient mouthpiece, to help control the loss of aerosol, and thereby reduce waste. The device is simply constructed of two molded plastic members, which are readily engaged to complete its assembly.Type: GrantFiled: July 6, 2000Date of Patent: April 2, 2002Assignee: Clinical Technologies, Inc.Inventors: Dennis Forchione, Robert Johnson
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Patent number: 6063374Abstract: A recombinant human immunodeficiency virus (rHIV) and recombinant mammalian cell-line (packaging systems) and a method for treating infection of cells by human immuneodeficiency virus HIV. rHIV, such as rHIV-1, comprises of a gene construction which includes a foreign gene. The expression of this gene is activated in human cells in the presence of wild-type HIV. This gene product can cause cell death in the presence of an appropriate drug, e.g. Acyclovir. This gene product is typically a viral thymidine kinase. rHIV is so constructed that it is unable to replicate by itself due to the absence of a regulatory gene that is necessary for its replication, such as tat or rev or both. The recombinant mammalian cell-line packaging system comprises in its genome a recombinant gene construction which typically includes a functional regulatory gene from HIV which is missing from rHIV, such as the tat or rev genes or both.Type: GrantFiled: November 28, 1995Date of Patent: May 16, 2000Assignee: Clinical Technologies, Inc.Inventors: Syed Zaki Salahuddin, Nickolas Chelyapov
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Patent number: 5814015Abstract: A processor driven syringe pump for one or more, typically two syringes, which are held vertically in corresponding pumping stations of a housing unit which itself is typically suspended from an IV pole. The pump features a central display having portions corresponding to each of the syringes operated by the pump. A data entry knob cooperative with a display processor, causes a cursor issue on the display to step through and choose the menu selections. A function knob is operative to select five operating states including: Purge, Setup, Stop, Run and Bolus in a virtual or software driven manner. The syringe holding station includes a pusher assembly having plunger clamp assembly and a load cell to measure force exerted on the plunger flange. An actuation pad and associated linkage provides for easy syringe flange capturing, while a syringe barrel clamp provides for easy syringe loading and secure syringe barrel positioning for many sizes of syringe.Type: GrantFiled: February 24, 1995Date of Patent: September 29, 1998Assignee: Harvard Clinical Technology, Inc.Inventors: Diane A. Gargano, Eric J. Flachbart, Barry Cowen, Monica Duh, John L. Rudser, Jr., Ken Zhen, Lynn Noble, Julian Warhurst, Luis Pedraza
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Patent number: 5753490Abstract: A recombinant human immunodeficiency virus (rHIV) and recombinant mammalian cell-line (packaging systems) and a method for treating infection of cells by human immuneodeficiency virus HIV. rHIV, such as rHIV-1, comprises of a gene construction which includes a foreign gene. The expression of this gene is activated in human cells in the presence of wild-type HIV. This gene product can cause cell death in the presence of an appropriate drug, e.g. Acyclovir. This gene product is typically a viral thymidine kinase. rHIV is so constructed that it is unable to replicate by itself due to the absence of a regulatory gene that is necessary for its replication, such as tat or rev or both. The recombinant mammalian cell-line packaging system comprises in its genome a recombinant gene construction which typically includes a functional regulatory gene from HIV which is missing from rHIV, such as the tat or rev genes or both.Type: GrantFiled: November 28, 1995Date of Patent: May 19, 1998Assignee: Clinical Technologies, Inc.Inventors: Syed Zaki Salahuddin, Nickolas Chelyapov