Patents Assigned to CMC BIOLOGICS A/S
  • Chromatography system and method for capturing a biopolymer
    Patent number: 11965018
    Abstract: The present invention relates to a chromatography system wherein the chromatography system comprises an eluting system and a capturing system consisting of at least two chromatography units operated alone or in series and a capturing process employing in-line buffer dilution in, which concentrated buffers are blended with water and provided to the chromatography units.
    Type: Grant
    Filed: January 29, 2022
    Date of Patent: April 23, 2024
    Assignee: CMC BIOLOGICS A/S
    Inventors: Simon Bergmann, Mads Laustsen
  • BIOREACTOR ARRANGEMENT AND CONTINUOUS PROCESS FOR PRODUCING AND CAPTURING A BIOPOL YMER
    Publication number: 20220185868
    Abstract: Provided is a bioreactor arrangement for producing a biopolymer expressed by a cell and a continuous process for a capturing the biopolymer employing two chromatography units operated in series or independently.
    Type: Application
    Filed: February 16, 2022
    Publication date: June 16, 2022
    Applicant: CMC BIOLOGICS A/S
    Inventors: Mads LAUSTSEN, Simon BERGMANN
  • Bioreactor arrangement and continuous process for producing and capturing a biopolymer
    Patent number: 11286292
    Abstract: The present invention relates to a bioreactor arrangement for producing a biopolymer expressed by a cell and a continuous process for a capturing the biopolymer employing two chromatography units operated in series or independently.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: March 29, 2022
    Assignee: CMC BIOLOGICS A/S
    Inventors: Mads Laustsen, Simon Bergmann
  • Chromatography system and method for capturing a biopolymer
    Patent number: 11267869
    Abstract: The present invention relates to a chromatography system (20) wherein the chromatography system comprises an eluting system (10) and a capturing system (11) consisting of at least two chromatography units (2,3) operated alone or in series and a capturing process employing in-line buffer dilution in, which concentrated buffers are blended with water and provided to the chromatography units.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: March 8, 2022
    Assignee: CMC BIOLOGICS A/S
    Inventors: Simon Bergmann, Mads Laustsen
  • High density fill and draw fermentation process
    Patent number: 10844345
    Abstract: The present invention relates to a high cell density fermentation fill and draw process for producing a product in a bioreactor system wherein during the fermentation, medium comprising impurities is removed via the impurity filter unit while new fresh medium is added to the cell culture vessel to replenish consumed nutrients and expelled medium.
    Type: Grant
    Filed: April 14, 2015
    Date of Patent: November 24, 2020
    Assignee: CMC BIOLOGICS A/S
    Inventor: Mads Laustsen
  • Method for producing a product (e.g. polypeptide) in a continuous cell culture fermentation process
    Patent number: 10717958
    Abstract: A method for improving productivity in microbial fermentations and mammalian cell culture bioreactors.
    Type: Grant
    Filed: May 1, 2019
    Date of Patent: July 21, 2020
    Assignee: CMC BIOLOGICS A/S
    Inventor: Mads Laustsen
  • METHOD FOR PRODUCING A PRODUCT (E.G. POLYPEPTIDE) IN A CONTINUOUS CELL CULTURE FERMENTATION PROCESS
    Publication number: 20190264154
    Abstract: A method for improving productivity in microbial fermentations and mammalian cell culture bioreactors.
    Type: Application
    Filed: May 1, 2019
    Publication date: August 29, 2019
    Applicant: CMC BIOLOGICS A/S
    Inventor: Mads LAUSTSEN
  • Method for producing a product (e.g. polypeptide) in a continuous cell culture fermentation process
    Patent number: 10316282
    Abstract: A method for improving productivity in microbial fermentations and mammalian cell culture bioreactors.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: June 11, 2019
    Assignee: CMC BIOLOGICS A/S
    Inventor: Mads Laustsen
  • BIOREACTOR SYSTEM AND METHOD FOR PRODUCING A BIOPOL YMER
    Publication number: 20180251716
    Abstract: Provided is a bioreactor system and a fermentation process employing continuous inline medium dilution in which concentrated medium and nutrients are blended with water or buffer and fed to the cell culture vessel of a bioreactor system, e.g. for production of antibodies and other recombinant proteins by mammalian cells.
    Type: Application
    Filed: May 5, 2018
    Publication date: September 6, 2018
    Applicant: CMC Biologics A/S
    Inventors: Mads LAUSTSEN, Adrian Blackburn
  • A High Density Fill and Draw Fermentation Process
    Publication number: 20170067010
    Abstract: The present invention relates to a high cell density fermentation fill and draw process for producing a product in a bioreactor system wherein during the fermentation, medium comprising impurities is removed via the impurity filter unit while new fresh medium is added to the cell culture vessel to replenish consumed nutrients and expelled medium.
    Type: Application
    Filed: April 14, 2015
    Publication date: March 9, 2017
    Applicant: CMC BIOLOGICS A/S
    Inventor: Mads LAUSTSEN
  • A BIOREACTOR ARRANGEMENT AND CONTINUOUS PROCESS FOR PRODUCING AND CAPTURING A BIOPOLYMER
    Publication number: 20160349220
    Abstract: The present invention relates to a bioreactor arrangement for producing a biopolymer expressed by a cell and a continuous process for a capturing the biopolymer employing two chromatography units operated in series or independently.
    Type: Application
    Filed: January 29, 2015
    Publication date: December 1, 2016
    Applicant: CMC BIOLOGICS A/S
    Inventors: Mads LAUSTSEN, Simon BERGMANN
  • A CHROMATOGRAPHY SYSTEM AND METHOD FOR CAPTURING A BIOPOLYMER
    Publication number: 20160347823
    Abstract: The present invention relates to a chromatography system (20) wherein the chromatography system comprises an eluting system (10) and a capturing system (11) consisting of at least two chromatography units (2,3) operated alone or in series and a capturing process employing in-line buffer dilution in, which concentrated buffers are blended with water and provided to the chromatography units.
    Type: Application
    Filed: January 29, 2015
    Publication date: December 1, 2016
    Applicant: CMC BIOLOGICS A/S
    Inventors: Simon BERGMANN, Mads LAUSTSEN
  • A BIOREACTOR SYSTEM AND METHOD FOR PRODUCING A BIOPOL YMER
    Publication number: 20160298072
    Abstract: Provided is a bioreactor system and a fermentation process employing continuous inline medium dilution in which concentrated medium and nutrients are blended with water or buffer and fed to the cell culture vessel of a bioreactor system, e.g. for production of antibodies and other recombinant proteins by mammalian cells.
    Type: Application
    Filed: November 19, 2014
    Publication date: October 13, 2016
    Applicant: CMC BIOLOGICS A/S
    Inventor: Mads LAUSTSEN
  • A METHOD FOR PRODUCING A PRODUCT (E.G. POLYPEPTIDE) IN A CONTINUOUS CELL CULTURE FERMENTATION PROCESS
    Publication number: 20160281044
    Abstract: A method for improving productivity in microbial fermentations and mammalian cell culture bioreactors.
    Type: Application
    Filed: March 11, 2014
    Publication date: September 29, 2016
    Applicant: CMC BIOLOGICS A/S
    Inventor: Mads LAUSTSEN
  • Method for producing a biopolymer (e.g. polypeptide) in a continuous fermentation process
    Patent number: 8679778
    Abstract: A method for improving productivity in microbial fermentations and mammalian cell culture bioreactors.
    Type: Grant
    Filed: June 11, 2008
    Date of Patent: March 25, 2014
    Assignee: CMC Biologics A/S
    Inventor: Mads Laustsen
  • Method For Producing a Biopolymer (e.g. polypeptide) In A Continuous Fermentation Process
    Publication number: 20100184149
    Abstract: A method for improving productivity in microbial fermentations and mammalian cell culture bioreactors.
    Type: Application
    Filed: June 11, 2008
    Publication date: July 22, 2010
    Applicant: CMC BIOLOGICS A/S
    Inventor: Mads Laustsen