Abstract: A device is provided for studying the ability of at least one mouse to find its bearings in a maze, the device including a plurality of houses distributed around a central agora and in which at least one stimulator allows the at least one mouse to carry out certain activities and/or satisfy certain primary needs. Each house further includes at least one sensor for measuring the activity of the mouse in the house, and more particularly its use of the at least one stimulator. Finally, a sensor makes it possible to detect and measure the movements of each mouse in the device. Quantitative parameters originating from these measurements thus make it possible to highlight the quality of the geographical memory of the at least one mouse.

Abstract: The present invention relates to the abietane diterpene taxodione and to rosemary stem extract containing taxodione for their use in treating a muscle wasting diseases and/or disorders; it also relates to the use of taxodione as natural meat preserver.

Abstract: The present invention relates to inhibitors of gangliosides metabolism for treating motor neuron diseases, in particular hereditary spastic paraplegias.

Abstract: A compound of following formula (I): where: X is O or S; A is an aromatic (hetero)cycle having 5 to 10 atoms selected from among carbon and nitrogen atoms, optionally being substituted; R? is H or (C1-C6)alkyl group; R1, R2, R3, R4 and R5, the same or different, are selected from the group formed by: H, (C1-C6)alkyl groups and (C6-C10)aryl groups. The compound is for the treatment of neurodegenerative diseases.

Abstract: Device for assisting crawling of an infant (2) on a training surface comprising: - a platform (1) comprising a chest supporting surface for supporting a chest of the infant (2) resting on the platform (1) in a prone position, and - rolling elements (9) rotatably mounted on the platform in such a way they can rotate 360 degrees (1) and arranged to be located between the platform (1) and the training surface, wherein the platform (1) is shaped so that, when the rolling elements (9) are in contact with the training surface, the chest supporting surface of the platform (1) is inclined relative to the training surface, so that the pelvis and the legs of the infant (2) are in contact with the training surface.

Abstract: Device for assisting crawling of an infant (2) on a training surface comprising: —a platform (1) comprising a chest supporting surface for supporting a chest of the infant (2) resting on the platform (1) in a prone position, and —rolling elements (9) rotatably mounted on the platform in such a way they can rotate 360 degrees (1) and arranged to be located between the platform (1) and the training surface, wherein the platform (1) is shaped so that, when the rolling elements (9) are in contact with the training surface, the chest supporting surface of the platform (1) is inclined relative to the training surface, so that the pelvis and the legs of the infant (2) are in contact with the training surface.

Abstract: The invention relates to a material that can be used as a bone substitute and to a method for the preparation thereof. The material comprises an organic phase (I) comprising striated collagen fibrils constituted of collagen I triple helices, said fibrils being organized over a large distance according to a 3D geometry associating aligned domains and cholesteric domains, and also isotropic domains where they are not organized; and a mineral phase (II) comprising apatite crystals having a hexagonal crystalline structure, space group 6/m, comprising at least calcium ions and phosphate ions; the axis c of said apatite crystals of the mineral phase is coaligned with the longitudinal axis of the striated collagen fibrils of the organic phase and the collagen content in the material is at least 75 mg/cm3.