Patents Assigned to COLLABORATIVE MEDICINAL DEVELOPMENT LLC
  • METHODS OF EXTENDING LIFESPAN BY ADMINISTERING FERROPTOSIS INHIBITORS
    Publication number: 20230172940
    Abstract: Provided herein is a method of extending the lifespan of an organism comprising administering to the organism an effective amount of a ferroptosis inhibitor. Also provided are compositions for extending lifespan comprising ferroptosis inhibitors.
    Type: Application
    Filed: January 17, 2023
    Publication date: June 8, 2023
    Applicant: COLLABORATIVE MEDICINAL DEVELOPMENT, LLC
    Inventors: Ashley Bush, Craig Rosenfeld, Kay Noel
  • Heteroaromatic and Heterobicyclic Aromatic Derivatives for the Treatment of Ferroptosis-Related Disorders
    Publication number: 20220144826
    Abstract: The present application discloses heteroaromatic and heterobicyclic aromatic derivative compounds and compositions, and methods for treating ferroptosis-related disorders and diseases inpatients using the compounds and compositions as disclosed herein.
    Type: Application
    Filed: March 10, 2020
    Publication date: May 12, 2022
    Applicant: COLLABORATIVE MEDICINAL DEVELOPMENT, LLC
    Inventors: John Warner, Carmen Baldino, Laura Muollo, John Lee, Srinivasa Cheruku, Rowan Walker, James Siedlecki, John Proudfoot, Shawn Johnstone, Mehdi Numa, Craig Rosenfeld
  • Dihydro-6-azaphenalene derivatives for the treatment of CNS, oncological diseases and related disorders
    Patent number: 10047089
    Abstract: In one embodiment, the present application discloses 2-aza-, 2-oxa- and 2-thia-2,3-dihydro-6-azaphenalene compounds and compositions, and methods for treating a neurological disease in a patient in need thereof using the compounds and compositions as disclosed herein.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: August 14, 2018
    Assignee: Collaborative Medicinal Development, LLC
    Inventors: John C. Warner, Jeffery Allen Gladding, Srinivasa R. Cheruku, Dieu Nguyen, Jean R. Loebelenz, James J. Norman, Sambaiah Thota, John W. Lee, Craig Rosenfeld
  • Compositions and Methods for Extending Lifespan
    Publication number: 20170266174
    Abstract: In one embodiment, the present application discloses a method of reducing senescence in a mammal by reducing the concentration of non-ferritin iron within the mammal, comprising the administration of a therapeutically effective amount of an iron chelator or an antioxidant, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: August 21, 2015
    Publication date: September 21, 2017
    Applicant: COLLABORATIVE MEDICINAL DEVELOPMENT LLC
    Inventors: Ashley Bush, Gawain McColl