Abstract: An apparatus for removing a flip-off cap from a bottle for pharmaceutical substances, which enables automating the removal process in a pharmaceutical substance handling line and, at the same time, may be easy and inexpensive to manufacture. In an example the apparatus comprises a removal station in which a cap is removed from the bottle.

Abstract: A modular incubator comprising a housing structure divided into cells and having several incubator modules, each of which can be housed, in a removable manner, in a relative cell and is provided with an incubation chamber to incubate microbiological or cellular cultures. Each cell has a first group of connectors and each incubator module has a second group of connectors, each of which can be coupled to a corresponding connector of the first group of connectors of the relative cell when the incubator module is housed in said cell. The first group of connectors has at least one pneumatic connector communicating with at least one source of aeriform substance, and the second group of connectors has a corresponding pneumatic connector communicating with the relative incubation chamber to allow the aeriform substance to be introduced into the incubation chamber.

Abstract: A modular incubator comprising a housing structure divided into cells and having several incubator modules, each of which can be housed, in a removable manner, in a relative cell and is provided with an incubation chamber to incubate microbiological or cellular cultures. Each cell has a first group of connectors and each incubator module has a second group of connectors, each of which can be coupled to a corresponding connector of the first group of connectors of the relative cell when the incubator module is housed in said cell. The first group of connectors has at least one pneumatic connector communicating with at least one source of aeriform substance, and the second group of connectors has a corresponding pneumatic connector communicating with the relative incubation chamber to allow the aeriform substance to be introduced into the incubation chamber.

Abstract: The method provides: a first step, in which a radioactive fluid is conveyed from a source to a container; a second step, during which inert gas under pressure is conveyed towards the container; and a third step, during which, due to the action of the inert gas, the radioactive fluid is conveyed from the container to a bottle.

Abstract: A system for automatic production of radioisotopes includes an irradiation unit connectable to a cyclotron and having an electrolytic cell; a purification unit for purifying the radioisotope formed in the irradiation unit; two conduits for transferring an irradiated and electrodissolved target from the irradiation unit to the purification unit; and a central control unit for controlling both the operating units and the transfer means. The method for producing radioisotopes is such that the target carrier is not dissolved together with the irradiated target.

Abstract: A ventilation assembly for a machine for the preparation of radiopharmaceuticals. The ventilation assembly includes a suction apparatus and release apparatus for generating a circulation of air within a vacuum dispensing chamber, a product filling calibrator accommodated in the dispensing chamber and presenting a cavity accommodating a container to be filled with radiopharmaceutical, and a suction conduit adapted to connect a bottom portion of the accommodating cavity to the suction apparatus for creating a one-way flow in the accommodating cavity. Also, a machine that includes the ventilation assembly.

Abstract: A procedure for the preparation of radioisotopes consisting of a first step of electrodepositing a metallic isotope target to be irradiated on a target-holder element, a second step of irradiating the target, a third step of dissolving the target and a fourth set of purifying the radioisotope from the initial metallic isotope and from other possible radioactive and metallic impurities; the electrodeposition step in turn consisting of a dissolution operation in which the isotope to be irradiated is dissolved in a solution of HNO3 with concentration from 0.5 to 2.5 M, a pH buffering operation, and a recirculation operation, in which the solution obtained above is circulated at a rate from 0.5 to 3 within an electrolytic cell during the current output within the cell itself; the electrodeposition of the target to be irradiated occurs within the electrolytic cell during the recirculation operation.

Abstract: A ventilation assembly for a machine for the preparation of radiopharmaceuticals, consisting of suction means and release means for generating a circulation of air within a vacuum dispensing chamber, a product filling calibrator accommodated in the dispensing chamber and presenting a cavity accommodating a container to be filled with radiopharmaceutical, and a suction conduit adapted to connect a bottom portion of the accommodating cavity to the suction means for creating a one-way flow in the accommodating cavity.