Patents Assigned to Consolidated Pharmaceuticals, Limited
  • Melphalan derivatives
    Patent number: 5075108
    Abstract: A compound of formula I ##STR1## wherein R.sub.1 is of formula II ##STR2## wherein R.sub.4 and R.sub.5, which may be the same or different, are bromo, chloro, iodo or alkylsulphonyl;R.sub.2 is of formula III ##STR3## wherein R.sub.6 and R.sub.7, which may be the same or different, are H, alkyl, aryl, carboxy, hydroxy or amino and n is 0-10; andR.sub.3 is hydroxy or a group capable of being cleared and replaced by a radical having an antigen binding site or R.sub.3 is a radical having an antigen binding site.
    Type: Grant
    Filed: December 21, 1987
    Date of Patent: December 24, 1991
    Assignee: Consolidated Pharmaceuticals, Limited
    Inventors: Ian F. C. McKenzie, Geoffrey A. Pietersz, Mark Smyth