Abstract: Silicone hydrogel contact lenses are provided which have reduced modulus and contact angle properties, and which have acceptable wettabilities for use in daily wear and extended or continuous wear applications.

Abstract: Optically clear silicone hydrogel contact lenses are described that comprise a polymeric lens body that is the reaction product of a polymerizable composition comprising at least 25 wt. % of at least one hydroxyalkyl methacrylate; and at least 20 wt. % of at least one HEMA-compatible bifunctional polysiloxane comprising at least 6 siloxane groups and having an HLB value of at least 5 and/or a hydroxyl group content of at least 1 wt. %.

Abstract: Silicone hydrogel contact lenses that are derived from a polymerizable composition including at least one siloxane monomer and at least one hydrophobic ethylene glycol methyl ether methacrylate-containing monomer, or at least one hydrophilic vinyl ether-containing monomer, or both, wherein, when the at least one hydrophobic ethylene glycol methyl ether methacrylate-containing monomer is present in the polymerizable composition, it is present in an amount of from 1 to 20 unit parts by weight, and when the at least one hydrophilic vinyl ether-containing monomer is present in the polymerizable composition, it is present in an amount of from 1 to 20 unit parts by weight, are described. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.

Abstract: Methods, devices, and systems for moving wet ophthalmic lenses are described in which the ophthalmic lenses are first placed in wells of lens carriers and are centered by the structure of the wells. The carriers are then moved to a transfer module of a packaging system for transferring the ophthalmic lenses in blister packages. The transfer from the carriers to the blister packages are performed by a pick and place robot having pickup heads sized and configured for suctioning the ophthalmic lenses from the lens carriers.

Abstract: Ophthalmic device molds made from a first portion of a molding surface formed from a first polymer and a second portion of the molding surface formed from a second polymer are described. When combined, the first portion and the second portion of the molding surface form an entire molding surface suitable for molding an entire surface, such as an anterior surface or a posterior surface of an ophthalmic device. Methods of manufacturing ophthalmic devices using these molds, including contact lenses, are also described.

Abstract: Silicone hydrogel contact lenses having ophthalmically acceptable surface wettabilities are obtained from pre-extracted polymerized silicone hydrogel contact lens products having relatively large amounts of removable or extractable materials. The silicone hydrogel contact lenses can be obtained from non-polar resin based contact lens molds and without surface treatments or an interpenetrating polymeric network of a polymeric wetting agent. Related lens products, polymerizable compositions, and methods are also described.

Abstract: Miscible polymerizable compositions comprising at least one primary amine-containing methacrylate monomer, or at least one primary amine-containing methacrylamide monomer, in addition to 20-80 wt. % siloxane monomer, 20-80 wt. % hydrophilic monomer, cross-linking agent, and polymerization initiator, are described. These polymerizable compositions can be used to form silicone hydrogel contact lenses, and in methods of manufacturing silicone hydrogel contact lenses.

Abstract: Method and apparatus for manufacturing a contact lens comprising: dispensing a plurality of separate portions (24) of a liquid composition onto a contact lens mold section (12, 16), each separate portion of the liquid composition having a volume of less than about 1000 nano-liters.

Abstract: Contact lenses comprising phosphorylcholine groups release beneficial polyionic or guanidinium-containing agents.

Abstract: The present disclosure provides systems and methods to aid in the resupply of product arrays, such as contact lenses. In an aspect, this is accomplished by providing a physical product array to a reseller. Additionally, a computer-operated application is provided that displays a virtual representation of the physical product array. The reseller can then manipulate the virtual storage array to more easily identify the specific product slots in the array that need to be restocked, and the application can interact directly with an ordering system for the product manufacturer to submit orders for fulfillment. In an aspect, the application stores the product attributes for each slot of the product array, so that a simple visual inspection of the physical array can be translated into the proper product without a reseller having to determine product attributes for the specific array slots.

Abstract: Contact lenses comprising an ionic component are packaged with a beneficial cationic agent in a temperature-sensitive packaging solution and/or a low ionic strength packaging solution.

Abstract: A method is provided for manufacturing ophthalmically-acceptable, distortion-free silicone hydrogel contact lenses without the use of volatile organic solvents in the manufacturing process. The contact lenses are extract with an extraction liquid comprising an aqueous solution of a non-volatile organic solvent, such as ethyl lactate.

Abstract: Contact lenses comprising phosphorylcholine groups release beneficial polyionic or guanidinium-containing agents.

Abstract: A sealed contact lens package contains a sterile, unworn contact lens and a contact lens packaging solution comprising epsilon polylysine (?PLL). The ?PLL protects the contact lens from microbial contamination caused by handling the lens when it is removed from its package.

Abstract: Silicone hydrogel contact lenses are formed from the reaction product of a polymerizable composition comprising at least one acrylate-containing siloxane monomer, at least one hydrophilic vinyl-containing monomer, and at least one vinyl-containing cross-linking agent. The contact lenses have ophthalmically-acceptable ionoflux values and surface wettability, and can be manufactured without the use of volatile organic solvents.

Abstract: Methods of manufacturing contact lenses using ophthalmic lens molds having a molding surface comprising a thermoplastic polymer, the molding surface having a percent polarity from 3% to 20% and a surface energy from about 25 mN/m to about 40 mN/m to cast mold a polymerizable composition having a surface tension from about 20 mN/m to about 25 mN/m, wherein a surface energy differential of the surface tension of the polymerizable composition less the surface energy of the molding surface less than or equal to zero (0); and silicone hydrogel contact lens bodies so manufactured are described.

Abstract: Contact lenses comprising phosphorylcholine groups release beneficial polyionic or guanidinium-containing agents.

Abstract: Silicone hydrogel contact lenses are formed from the reaction product of a polymerizable composition comprising at least one acrylate-containing siloxane monomer, at least one hydrophilic vinyl-containing monomer, and at least one vinyl-containing cross-linking agent, wherein the polymerizable composition has a molar ratio of total amount of hydrophilic vinyl-containing monomer to total amount of acrylate-containing siloxane monomer of from 5:1 to 30:1, respectively. The silicone hydrogel contact lenses have good manufacturing processability, can be manufactured without the use of alcohol solvents, and have excellent surface wettability.

Abstract: Ophthalmic lens molds made from one or more thermoplastic polymers with average polarities from about 1% to about 7%, ophthalmic lenses including silicone hydrogel contact lenses molded using these less polar thermoplastic polymers, and related methods are described. When the molds are used to cast mold silicone hydrogel contact lenses, the resulting polymerized lens bodies have ophthalmically acceptably wettable surfaces.

Abstract: Silicone hydrogel contact lenses are formed from the reaction product of a polymerizable composition comprising at least one hydrophilic vinyl amide-containing monomer, at least one acrylate-containing siloxane monomer, and at least one hydrophilic vinyl ether-containing monomer. The contact lenses have ophthalmically-acceptable surface wettability and can be manufactured without the use of volatile organic solvents.