Abstract: A fatty acid-releasing contact lens is described as well as method of manufacturing the same. The fatty acid-releasing contact lens comprises a glycerophospholipid loaded to the polymeric lens body and sustains the release of C12-C26 fatty acid after 1 hour in a release media comprising an sPLA2 enzyme solution. The fatty acid-releasing contact lens can be comfortably worn by a contact lens wearer and can increase the duration of comfortable lens wearing time and/or reduce lens awareness events in a contact lens wearer.

Abstract: A contact lens (301) and methods of manufacturing such a lens (301) are described. The lens (301) includes an optic zone (302). The optic zone (302) comprises a central region (305), the central region (305) having a first optical axis, a centre of curvature that is on the first optical axis, and a diameter that is less than 2.0 mm. The optic zone (302) comprises an annular region (303). The annular region (303) comprises a plurality of concentric treatment zones (303a, 303b), wherein each treatment zone (303a, 303b) has a radial sagittal power profile that increases with increasing radial distance from the optical axis.

Abstract: An oleic acid-releasing contact lens is described as well as method of manufacturing the same. The oleic acid-releasing contact lens comprises a glycerophospholipid comprising an oleoyl group at the sn-2 position and sustains the release of oleic acid in the presence of sPLA2 enzyme present in human tears. The oleic acid-releasing contact lens can increase the duration of comfortable lens wearing time and/or reduce lens awareness events in a symptomatic contact lens wearer.

Abstract: A blister package for a contact lens includes a base sheet and a sealing sheet. Either the base sheet or the sealing sheet includes a bowl, and the other sheet includes a dome and a sealing surface. The dome has a radius of curvature of about 13 mm to 19 mm and a height of less than 7 mm relative to the sealing surface. The dome is configured to protrude into the bowl to form a cavity. Related methods are also described.

Abstract: A contact lens comprising one or more microchannels for transport of liquid through the lens is provided. The contact lens can be made by contacting a curable composition with a microfiber that is insoluble in the curable composition; curing the curable composition to provide a polymeric lens body with the microfiber embedded therein; and contacting the polymeric lens body with a solvent to dissolve the microfiber.

Abstract: A method of designing a fluid-filled contact lens (103) is described. The method involves generating a computational model that includes a fluid-filled lens (103) and the shape of a cornea causes deformation of an internal structure of the fluid-filled lens (103) to generate a deformed, fluid-filled lens (103) with altered optical properties. The method also includes modelling (5) the optical properties of the deformed, fluid-filled lens (103). The shape of the fluid-filled lens (103) is then adjusted (7) to reduce the effects of the deformation on the optical properties. This is referred to as an adjusted fluid-filled lens (103). A corresponding off-eye lens design is generated (110 based on the adjusted fluid-filled lens design.

Abstract: A WS12-releasing contact lens is described as well as method of manufacturing the same. The WS12-releasing contact lens comprises a polymeric lens body and WS12 releasably adhered to the polymeric lens body, and releases from 0.05 ?g to 0.5 ?g WS12 after 1 hour in a release media or when worn by a human subject. The WS12-releasing contact lens can be comfortably worn by a symptomatic contact lens wearer and can increase the duration of comfortable lens wearing time and/or reduce lens awareness events and/or reduce contact lens dryness in a symptomatic contact lens wearer.

Abstract: An ophthalmic lens for myopia control. A first surface of the lens varies across the lens to form a first surface power map. A second surface of the lens varies across the lens to form a second surface power map. Each of the first and second surface power maps comprise a spiral. The spirals formed by the first and second surface power maps twist in opposing directions. Related methods are also described.

Abstract: A contact lens package kit is described that includes a contact lens packages, wherein each contact lens package includes a base member having a cavity and a sealing member coupled to the base member. An unworn contact lens is provided in a packaging solution within the sealed cavity. The base member is a thermoplastic material (or other recyclable material) and includes a substantially planar surface surrounding the cavity to provide a sealing surface for the sealing member. The kit also includes at least one fastener configured to retain a plurality of base members from each of the contact lens packages after the contact lens is removed from the cavity. A recyclable thermoplastic contact lens assembly is also described, that includes empty contact lens packages attached to a fastener. A method to recycle used contact lens packages, such as curbside recycling, is further described that uses the fastener, and the fastener itself is also described.

Abstract: Contact lens packages are provided and each includes a base member having a cavity and a sealing member coupled to the base member. An unworn contact lens is provided in a packaging solution within the sealed cavity. The base member is a thermoplastic or other recyclable material. The base member includes at least one latch and at least one slot. The latch and slot are configured to connect to the slot and latch, respectively, of another base member, after the contact lenses are removed from the cavities. A recyclable thermoplastic contact lens assembly is also provided that includes empty contact lens package base members stacked and connected together. A method to recycle used contact lens package base members, such as by curbside recycling, is also provided.

Abstract: Contact lens packages are provided and each includes a base member having a cavity and a sealing member coupled to the base member. An unworn contact lens is provided in a packaging solution within the sealed cavity. The base member is a thermoplastic or other recyclable material. The base member includes at least one latch and at least one slot. The latch and slot are configured to connect to the slot and latch, respectively, of another base member, after the contact lenses are removed from the cavities. A recyclable thermoplastic contact lens assembly is also provided that includes empty contact lens package base members stacked and connected together. A method to recycle used contact lens package base members, such as by curbside recycling, is also provided.

Abstract: Contact lens packages are provided and each includes a base member having a cavity and a sealing member coupled to the base member. An unworn contact lens is provided in a packaging solution within the sealed cavity. The base member is a thermoplastic or other recyclable material. The base member includes at least one latch and at least one slot. The latch and slot are configured to connect to the slot and latch, respectively, of another base member, after the contact lenses are removed from the cavities. A recyclable thermoplastic contact lens assembly is also provided that includes empty contact lens package base members stacked and connected together. A method to recycle used contact lens package base members, such as by curbside recycling, is also provided.

Abstract: A WS12-releasing contact lens is described as well as method of manufacturing the same. The WS12-releasing contact lens comprises a polymeric lens body and WS12 releasably adhered to the polymeric lens body, and releases from 0.05 ?g to 0.5 ?g WS12 after 1 hour in a release media or when worn by a human subject. The WS12-releasing contact lens can be comfortably worn by a symptomatic contact lens wearer and can increase the duration of comfortable lens wearing time and/or reduce lens awareness events and/or reduce contact lens dryness in a symptomatic contact lens wearer.

Abstract: A blister package for a contact lens is provided. A deformable slider supporting a lens is movable via pull-tab or hinge to lift the contact lens out of a lens well. The deformable slider can include a hinge connected to a flexible peel-away top of the blister package or connected to a pull tab that can be pulled to pull taut the deformable slider. A blister package is also provided that includes a hinged shell having a lateral opening opposite the hinge, and a deformable slider that is folded over onto itself and seals both a top chamber and a bottom chamber. By pulling a tongue of the deformable slider, which extends from the lateral opening, the deformable slider can be removed from the closed shell and the closed shell can be opened enabling access to the contact lens.

Abstract: A contact lens package kit is described that includes a contact lens packages, wherein each contact lens package includes a base member having a cavity and a sealing member coupled to the base member. An unworn contact lens is provided in a packaging solution within the sealed cavity. The base member is a thermoplastic material (or other recyclable material) and includes a substantially planar surface surrounding the cavity to provide a sealing surface for the sealing member. The kit also includes at least one fastener configured to retain a plurality of base members from each of the contact lens packages after the contact lens is removed from the cavity. A recyclable thermoplastic contact lens assembly is also described, that includes empty contact lens packages attached to a fastener. A method to recycle used contact lens packages, such as curbside recycling, is further described that uses the fastener, and the fastener itself is also described.

Abstract: A flexible optical element adopting liquid crystals (LCs) as the materials for realizing electrically tunable optics is foldable. A method for manufacturing the flexible element includes patterned photo-polymerization. The LC optics can include a pair of LC layers with orthogonally aligned LC directors for polarizer-free properties, flexible polymeric alignment layers, flexible substrates, and a module for controlling the electric field. The lens power of the LC optics can be changed by controlling the distribution of electric field across the optical zone.

Abstract: Methods of manufacturing an ophthalmic lens are described. The methods include a step of providing an ophthalmic lens; and a step of providing a photocurable film. The methods use a digital light projections system to photocure at least one region of the film to produce at least one photocured gradient index refractive element. The film is applied to a surface of the lens.

Abstract: A contact lens (101), the lens (101) including an optic zone (102). The optic zone (102) comprises a central region (105), the central region (105) having a centre of curvature that is on an optical axis (119). The optic zone (102) comprises a first annular region (103). The first annular region (103) has an off-axis centre of curvature that is a first distance from the optical axis (119). The first annular region (103) has a sagittal power profile that increases with increasing radial distance from the optical axis (119) with a gradient of between 1.0 D/mm and 20.0 D/mm. At a point halfway across the width of the first annular region (103), the sagittal power matches the average radial sagittal power of the central region (105).

Abstract: A cationic contact lens is described as well as methods of manufacturing the same. The cationic contact lens includes a polymeric lens body that is the reaction product of a polymerizable composition that includes at least one siloxane, at least one nonionic hydrophilic monomer and at least one acyclic tertiary amine monomer. The cationic contact lens can be an unworn sterile silicone hydrogel contact lens. The contact lens is capable of substantially linear release of a releasable anionic agent and the at least one acyclic tertiary amine monomer facilitates uptake and/or sustained release of the releasable anionic agent by the polymeric lens body. The contact lens can be present in a sealed contact lens package.

Abstract: Contact lens packages are provided and each includes a base member having a cavity and a sealing member coupled to the base member. An unworn contact lens is provided in a packaging solution within the sealed cavity. The base member is a thermoplastic or other recyclable material. The base member includes at least one connecting member that can be an interlocking feature and/or a stackable feature. The connecting member is configured to connect to the connecting member of another base member, after the contact lenses are removed from the cavities. A recyclable thermoplastic contact lens assembly is also provided that includes empty contact lens package base members stacked and connected together. A method of manufacturing contact lens packages and a method to recycle used contact lens package base members, such as by curbside recycling, are also provided.