Patents Assigned to Curacyte AG
  • Inhibitors for the blood-clotting factor Xa
    Patent number: 6841701
    Abstract: The invention relates to derivatives of amidino-benzylamine, especially derivatives of 4-amidino-benzylamine, with two bonded amino acids. These derivatives represent a novel group of highly active and very selective F Xa-inhibitors for treating cardiovascular diseases and thrombotic events.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: January 11, 2005
    Assignee: Curacyte AG
    Inventors: Jörg Stürzebecher, Torsten Steinmetzer, Sebastian Künzel, Andrea Schweinitz
  • Urokinase inhibitors
    Patent number: 6831196
    Abstract: The invention relates to a highly active, highly specific urokinase inhibitor which is suitable for therapeutic applications and can be synthesized in an extremely simple manner. Surprisingly, it was found that amidino benzylamine derivatives, especially 4-amidino-benzylamine, with two bonded amino acids represent a new group of highly active and very selective uPA inhibitors. The urokinase inhibitors can be used in medical applications, e.g. in the treatment of malign tumors such as in cases of metastatic spread.
    Type: Grant
    Filed: December 9, 2002
    Date of Patent: December 14, 2004
    Assignee: Curacyte AG
    Inventors: Jörg Stürzebecher, Torsten Steinmetzer, Andrea Schweinitz