Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of Olig2. Also described herein are methods of using such Olig2 inhibitors, alone and in combination with other compounds, for treating cancer and other diseases. In particular the Olig2 inhibitors may be used to treat glioblastoma.
Type:
Grant
Filed:
July 2, 2021
Date of Patent:
July 4, 2023
Assignee:
CURTANA PHARMACEUTICALS, INC.
Inventors:
Graham Beaton, Fabio C. Tucci, Satheesh B. Ravula, Stanton F. McHardy, Francisco Xavier Ruiz, Ambrosio Lopez, Bismarck Campos, Hua-Yu Leo Wang
Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of Olig2. Also described herein are methods of using such Olig2 inhibitors, alone and in combination with other compounds, for treating cancer and other diseases. In particular the Olig2 inhibitors may be used to treat glioblastoma.
Type:
Grant
Filed:
February 28, 2019
Date of Patent:
June 27, 2023
Assignee:
CURTANA PHARMACEUTICALS, INC.
Inventors:
Graham Beaton, Stanton F. McHardy, Ambrosio Lopez, Jr., Bismarck Campos, Hua-Yu Leo Wang
Abstract: Described herein are urea compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of Olig2. Also described herein are methods of using such Olig2 inhibitors, alone and in combination with other compounds, for treating cancer and other diseases. In particular the Olig2 inhibitors may be used to treat glioblastoma.
Type:
Grant
Filed:
August 25, 2017
Date of Patent:
February 8, 2022
Assignee:
CURTANA PHARMACEUTICALS, INC.
Inventors:
Graham Beaton, Stanton F. McHardy, Ambrosio Lopez, Jr., Bismarck Campos, Hua-Yu Leo Wang
Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of Olig2. Also described herein are methods of using such Olig2 inhibitors, alone and in combination with other compounds, for treating cancer and other diseases. In particular the Olig2 inhibitors may be used to treat glioblastoma.
Type:
Grant
Filed:
February 10, 2016
Date of Patent:
March 12, 2019
Assignee:
CURTANA PHARMACEUTICALS, INC.
Inventors:
Graham Beaton, Fabio Tucci, Satheesh B. Ravula, Hua-Yu Wang