Abstract: A method of making a miniature chamber assembly that provides a miniature capillary environment in which a liquid medium containing microscopic size particulate material can be placed for study under a microscope includes the steps of forming components which are inadequate as to wettability relative to the liquid medium, altering the wettability of the components relative to the liquid medium so that they can provide a miniaturized capillary environment that can contain the liquid medium with particulate material for a time sufficient to prevent deterioration while being studied, and assembling the components to define the miniaturized capillary environment.