Patents Assigned to Dalian Zhen-Ao Pharmaceutical Co., Ltd.
  • Patent number: 8940865
    Abstract: Disclosed are two myocardial peptides, whose amino acid sequences are Trp-Ser-Asn-Val-Leu-Arg-Gly-Met-Gly-Gly-Ala-Phe and Lys-Gly-Ala-Trp-Ser-Asn-Val-Leu-Arg-Gly-Met-Gly-Gly-Ala-Phe respectively, wherein the latter can be obtained by extracting from myocardial peptides solution. The myocardial peptides can be used in the produce of a medicament for preventing and/or treating myocardial ischemia.
    Type: Grant
    Filed: July 15, 2008
    Date of Patent: January 27, 2015
    Assignee: Dalian Zhen-Ao Pharmaceutical Co, Ltd.
    Inventors: Yusong Chen, Shu Li, Risheng Wang, Qiang Liang, Zheng Zeng, Xiaohong Qian, Dong Cao, Huimin Liang
  • Publication number: 20110160432
    Abstract: Disclosed are two myocardial peptides, whose amino acid sequences are Trp-Ser-Asn-Val-Leu-Arg-Gly-Met-Gly-Gly-Ala-Phe and Lys-Gly-Ala-Trp-Ser-Asn-Val-Leu-Arg-Gly-Met-Gly-Gly-Ala-Phe respectively, wherein the latter can be obtained by extracting from myocardial peptides solution. The myocardial peptides can be used in the produce of a medicament for preventing and/or treating myocardial ischemia.
    Type: Application
    Filed: July 15, 2008
    Publication date: June 30, 2011
    Applicant: DALIAN ZHEN-AO PHARMACEUTICAL CO., LTD.
    Inventors: Yusong Chen, Shu Li, Risheng Wang, Qiang Liang, Zheng Zeng, Xiaohong Qian, Dong Cao, Huimin Liang
  • Patent number: 7427663
    Abstract: The present invention relates to a cardio myopeptidin which is isolated from the hearts of non-human healthy mammals. The molecular weight of the cardio myopeptidin is less than 10000 Dalton, the peptide content thereof being 75%˜90%, the free amino acid content 6%˜15%, the ribonucleic acid content less than 2%, and the deoxyribonucleic acid content less than 7.5%. The present invention further provides a method of producing the cardio myopeptidin and the use thereof in producing pharmaceuticals for treating cardiac disorders, specifically the use in producing pharmaceuticals for treating myocardial ischemic and reperfusion injury. The cardio myopeptidin of the present invention can work directly on myocytes, promoting the repair of injuries caused by various reasons, and providing a new way to relieve ischemic and reperfusion injury, and to promote the repair of injured myocardium.
    Type: Grant
    Filed: February 23, 2004
    Date of Patent: September 23, 2008
    Assignee: Dalian Zhen-Ao Pharmaceutical Co., Ltd.
    Inventors: Yusong Chen, Shu Li
  • Publication number: 20070117745
    Abstract: The present invention relates to a cardio myopeptidin which is isolated from the hearts of non-human healthy mammals. The molecular weight of the cardio myopeptidin is less than 10000 Dalton, the peptide content thereof being 75%˜90%, the free amino acid content 6%˜15%, the ribonucleic acid content less than 2%, and the deoxyribonucleic acid content less than 7.5%. The present invention further provides a method of producing the cardio myopeptidin and the use thereof in producing pharmaceuticals for treating cardiac disorders, specifically the use in producing pharmaceuticals for treating myocardial ischemic and reperfusion injury. The cardio myopeptidin of the present invention can work directly on myocytes, promoting the repair of injuries caused by various reasons, and providing a new way to relieve ischemic and reperfusion injury, and to promote the repair of injured myocardium.
    Type: Application
    Filed: February 23, 2004
    Publication date: May 24, 2007
    Applicant: DALIAN ZHEN-AO PHARMACEUTICAL CO., LTD.
    Inventors: Yusong Chen, Shu Li